NFL Injury
Team Injury
| Team | Player | Pos | Injury | Status |
|---|---|---|---|---|
| CAR | Jaycee Horn | CB | Head | Questionable for Wild Card vs L.A. Rams |
| CHI | T.J. Edwards | LB | Lower Leg | Out for Wild Card vs Green Bay |
| CHI | Andrew Billings | DT | Hip | Questionable for Wild Card vs Green Bay |
| CHI | Ozzy Trapilo | OT | Knee | Out for Wild Card vs Green Bay |
| GB | Zach Tom | G | Back | Inactive for Wild Card at Chicago |
| GB | Edgerrin Cooper | LB | Ankle | Questionable for Wild Card at Chicago |
| GB | Jacob Monk | C | Biceps | Questionable for Wild Card at Chicago |
| LAR | Darious Williams | CB | Coach's Decision | Inactive for Wild Card at Carolina |
| LAR | Matthew Stafford | QB | Finger | Questionable for Wild Card at Carolina |
| PIT | Isaiahh Loudermilk | DT | Ankle | IR. Injured Reserve |
| BUF | Josh Palmer | WR | Ankle | IR. Injured Reserve |
| CAR | Krys Barnes | LB | Coach's Decision | Inactive for Wild Card vs L.A. Rams |
| CAR | Ikem Ekwonu | OT | Knee | Questionable for Wild Card vs L.A. Rams |
| CAR | Robert Hunt | OT | Pectoral | Questionable for Wild Card vs L.A. Rams |
| CAR | Nick Samac | C | Coach's Decision | Inactive for Wild Card vs L.A. Rams |
| CAR | Tershawn Wharton | DE | Hamstring | Questionable for Wild Card vs L.A. Rams |
| CAR | LaBryan Ray | DT | Coach's Decision | Inactive for Wild Card vs L.A. Rams |
| CAR | Chandler Zavala | G | Calf | IR. Injured Reserve |
| CAR | Jared Harrison-Hunte | DE | Coach's Decision | Inactive for Wild Card vs L.A. Rams |
| CHI | Case Keenum | QB | Coach's Decision | Inactive for Wild Card vs Green Bay |
| CHI | Amen Ogbongbemiga | LB | Concussion | Inactive for Wild Card vs Green Bay |
| CHI | Chauncey Gardner-Johnson | SAF | Concussion | Inactive for Wild Card vs Green Bay |
| CHI | Luke Newman | G | Coach's Decision | Inactive for Wild Card vs Green Bay |
| CHI | Kyler Gordon | CB | Groin | Questionable for Wild Card vs Green Bay |
| CHI | Jahdae Walker | WR | Coach's Decision | Inactive for Wild Card vs Green Bay |
| CHI | Braxton Jones | OT | Knee | IR. Injured Reserve |
| CHI | R. Hyppolite II | LB | Coach's Decision | Inactive for Wild Card vs Green Bay |
| CHI | Joe Tryon-Shoyinka | DE | Concussion | Inactive for Wild Card vs Green Bay |
| GB | Collin Oliver | LB | Coach's Decision | Inactive for Wild Card at Chicago |
| GB | Jakobie Keeney-James | WR | Coach's Decision | Inactive for Wild Card at Chicago |
| GB | Jaylin Simpson | CB | Coach's Decision | Inactive for Wild Card at Chicago |
| GB | Dontayvion Wicks | WR | Concussion | Inactive for Wild Card at Chicago |
| HOU | Jawhar Jordan | RB | Ankle | Out for Wild Card at Pittsburgh |
| LAC | Tucker Fisk | TE | Ankle | Questionable for Wild Card at New England |
| LAC | KeAndre Lambert-Smith | WR | Hamstring | IR. Injured Reserve |
| LAR | Jordan Whittington | WR | Knee | Inactive for Wild Card at Carolina |
| LAR | Ahkello Witherspoon | CB | Shoulder | Questionable for Wild Card at Carolina |
| LAR | Kevin Dotson | OG | Ankle | Inactive for Wild Card at Carolina |
| LAR | Derion Kendrick | CB | Coach's Decision | Inactive for Wild Card at Carolina |
| LAR | Josh Wallace | CB | Ankle | Inactive for Wild Card at Carolina |
| LAR | Stetson Bennett | QB | Coach's Decision | Inactive for Wild Card at Carolina |
| LAR | Terrance Ferguson | TE | Hamstring | Inactive for Wild Card at Carolina |
| NE | Alex Austin | CB | Wrist | IR. Injured Reserve |
| PHI | Azeez Ojulari | LB | Hamstring | IR. Injured Reserve |
| PHI | Brett Toth | G | Concussion | Out for Wild Card vs San Francisco |
| SF | Jacob Cowing | WR | Hamstring | IR. Injured Reserve |
| ATL | Troy Andersen | LB | Knee | Physically Unable to Perform |
| BUF | Matt Prater | K | Quadriceps | Questionable for Wild Card at Jacksonville |
| BUF | Damar Hamlin | SAF | Pectoral | IR. Injured Reserve |
| BUF | Terrel Bernard | LB | Calf | Out for Wild Card at Jacksonville |
| CAR | Jonathon Brooks | RB | Knee - ACL | Physically Unable to Perform |
| CIN | Erick All | TE | Knee - ACL | Physically Unable to Perform |
| CLE | Deshaun Watson | QB | Achilles | Physically Unable to Perform |
| CLE | Jeremiah Owusu-Koramoah | LB | Neck | Physically Unable to Perform |
| DET | Levi Onwuzurike | DT | Knee - ACL | Physically Unable to Perform |
| GB | John Williams | OG | Back | Physically Unable to Perform |
| HOU | Jimmie Ward | SAF | Foot | Physically Unable to Perform. Expected Return - Week 19 |
| HOU | Tank Dell | WR | Knee - ACL + MCL | Physically Unable to Perform |
| HOU | Kurt Hinish | DT | Undisclosed | Physically Unable to Perform. Expected Return - Week 19 |
| JAC | Cooper Hodges | OT | Knee | Physically Unable to Perform. Expected Return - Week 19 |
| LAC | Savion Washington | OT | Undisclosed | Physically Unable to Perform |
| LAC | Kendall Williamson | SAF | Ankle | Out for Wild Card at New England |
| MIA | Liam Eichenberg | OT | Knee | Physically Unable to Perform |
| MIN | Gavin Bartholomew | TE | Back | Physically Unable to Perform |
| NE | Kayshon Boutte | WR | Hamstring | Questionable for Wild Card vs L.A. Chargers |
| NE | Khyiris Tonga | DT | Foot | Out for Wild Card vs L.A. Chargers |
| NYG | A. Johnson Jr. | SAF | Undisclosed | Physically Unable to Perform |
| NYJ | Irvin Charles | WR | Knee - ACL | Physically Unable to Perform |
| PIT | Jonnu Smith | TE | Lower Body | — |
| SF | Renardo Green | CB | Ankle | Questionable for Wild Card at Philadelphia |
| BUF | Jordan Phillips | DT | Ankle | IR. Injured Reserve |
| GB | Elgton Jenkins | C | Lower Leg | IR. Injured Reserve |
| HOU | Jaylen Reed | SAF | Forearm | IR. Injured Reserve. Expected Return - Week 19 |
| HOU | Tytus Howard | OT | Ankle | — |
| HOU | D. Stingley Jr. | CB | Oblique | — |
| HOU | Sheldon Rankins | DT | Elbow | — |
| HOU | Denico Autry | DT | Knee | — |
| LAC | Austin Deculus | OT | Oblique | Questionable for Wild Card at New England |
| LAC | Del'Shawn Phillips | LB | Hamstring | Questionable for Wild Card at New England |
| LAC | Eric Rogers | CB | Undisclosed | IR. Injured Reserve |
| NE | Thayer Munford | OT | Knee | Questionable for Wild Card vs L.A. Chargers |
| NE | Vederian Lowe | OT | Illness | — |
| NE | Garrett Bradbury | C | Illness | — |
| NE | Terrell Jennings | RB | Concussion | IR. Injured Reserve |
| PIT | Jaylen Warren | RB | Illness | — |
| SF | Ben Bartch | OT | Foot | IR. Injured Reserve |
| BUF | Shaq Green-Thompson | OLB | Neck | Questionable for Wild Card at Jacksonville |
| BUF | Dalton Kincaid | TE | Knee | — |
| GB | Nick Niemann | LB | Pectoral | — |
| GB | Bo Melton | CB | Knee | IR. Injured Reserve |
| GB | Warren Brinson | DT | Foot | — |
| JAC | Montaric Brown | CB | Nose | — |
| JAC | G. Newsome II | CB | Shoulder | — |
| JAC | Danny Striggow | DE | Elbow | — |
| JAC | Jarrian Jones | CB | Illness | — |
| JAC | Jalen McLeod | LB | Ankle | IR. Injured Reserve |
| NO | Taysom Hill | TE | Shoulder - AC Joint | Questionable for start of Training Camp |
| SEA | Elijah Arroyo | TE | Knee | IR. Injured Reserve |
| SF | Tatum Bethune | LB | Groin | IR. Injured Reserve |
| SF | George Kittle | TE | Ankle | — |
| SF | Jordan Elliott | DT | Knee | — |
| SF | Keion White | DE | Groin | Questionable for Wild Card at Philadelphia |
| SF | Yetur Gross-Matos | DE | Knee | — |
| CHI | Kiran Amegadjie | OT | Elbow | IR. Injured Reserve |
| CHI | Roschon Johnson | RB | Thumb | IR. Injured Reserve |
| LAR | Rob Havenstein | OT | Ankle | IR. Injured Reserve |
| LAR | Shaun Dolac | LB | Knee - PCL | IR. Injured Reserve |
| ARI | Evan Brown | OG | Personal | Questionable for start of Training Camp |
| ATL | Ronnie Harrison | LB | Illness | Questionable for start of Training Camp |
| ATL | Brandon Dorlus | DE | Hamstring | Questionable for start of Training Camp |
| BAL | Rashod Bateman | WR | Illness | Questionable for start of Training Camp |
| BUF | Landon Jackson | DE | Knee | IR. Injured Reserve |
| BUF | Dorian Strong | CB | Neck | IR. Injured Reserve |
| BUF | Ed Oliver | DT | Knee - Meniscus | IR. Injured Reserve |
| BUF | DaQuan Jones | DT | Calf | — |
| BUF | Taylor Rapp | SAF | Knee | IR. Injured Reserve |
| BUF | Jordan Poyer | FS | Hamstring | — |
| BUF | Maxwell Hairston | CB | Ankle | Out for Wild Card at Jacksonville |
| BUF | Curtis Samuel | WR | Elbow | IR. Injured Reserve |
| BUF | Ty Johnson | RB | Ankle | Questionable for Wild Card at Jacksonville |
| CIN | Joseph Ossai | DE | Ankle | Questionable for start of Training Camp |
| CIN | Cam Grandy | TE | Chest | Questionable for start of Training Camp |
| CIN | Josh Newton | CB | Hamstring | Questionable for start of Training Camp |
| CIN | Charlie Jones | WR | Ankle | Questionable for start of Training Camp |
| CLE | H. Fannin Jr. | TE | Groin | Questionable for start of Training Camp |
| CLE | David Njoku | TE | Knee | Questionable for start of Training Camp |
| CLE | Kingsley Eguakun | C | Knee | Questionable for start of Training Camp |
| DAL | S. Revel Jr. | CB | Concussion | Questionable for start of Training Camp |
| DAL | DeMarvion Overshown | LB | Concussion | Questionable for start of Training Camp |
| DAL | Tyler Smith | OT | Knee | Questionable for start of Training Camp |
| DAL | Alijah Clark | SAF | Personal | Questionable for start of Training Camp |
| DEN | John Franklin-Myers | DE | Hip | Questionable for Divisional Playoffs |
| DEN | Dre Greenlaw | LB | Hamstring | Questionable for Divisional Playoffs |
| DET | Kayode Awosika | OG | Illness | Questionable for start of Training Camp |
| DET | Alex Anzalone | MLB | Concussion | Questionable for start of Training Camp |
| DET | Alim McNeill | DT | Abdomen | Questionable for start of Training Camp |
| DET | Thomas Harper | SAF | Concussion | Questionable for start of Training Camp |
| DET | Penei Sewell | OT | Ankle | Questionable for start of Training Camp |
| GB | Malik Willis | QB | Shoulder | — |
| HOU | Kamari Lassiter | CB | Ankle | — |
| HOU | Trent Brown | OT | Ankle | — |
| HOU | Jamal Hill | LB | Calf | — |
| IND | Sauce Gardner | CB | Calf | Questionable for start of Training Camp |
| IND | Will Mallory | TE | Chest | Questionable for start of Training Camp |
| JAC | Patrick Mekari | OT | Back | — |
| KC | Xavier Worthy | WR | Illness | Questionable for start of Training Camp |
| KC | Trey Smith | G | Ankle | Questionable for start of Training Camp |
| LAC | Elijah Molden | CB | Hamstring | Questionable for Wild Card at New England |
| LAC | Omarion Hampton | RB | Ankle | Questionable for Wild Card at New England |
| LV | Geno Smith | QB | Ankle | Questionable for start of Training Camp |
| LV | Dylan Parham | OG | Illness | Questionable for start of Training Camp |
| LV | Raheem Mostert | RB | Knee | Questionable for start of Training Camp |
| LV | Adam Butler | DT | Biceps | Questionable for start of Training Camp |
| MIA | Minkah Fitzpatrick | FS | Calf | Questionable for start of Training Camp |
| MIA | De'Von Achane | RB | Shoulder | Questionable for start of Training Camp |
| MIA | Austin Jackson | OT | Back | Questionable for start of Training Camp |
| MIA | Jaylen Waddle | WR | Ribs | Questionable for start of Training Camp |
| MIA | Chop Robinson | LB | Concussion | Questionable for start of Training Camp |
| MIN | Aaron Jones | RB | Hip | Questionable for start of Training Camp |
| MIN | T.J. Hockenson | TE | Shoulder | Questionable for start of Training Camp |
| MIN | Dwight McGlothern | CB | Hip | Questionable for start of Training Camp |
| MIN | Myles Price | WR | Ankle | Questionable for start of Training Camp |
| NE | Harold Landry | LB | Knee | Questionable for Wild Card vs L.A. Chargers |
| NE | Jared Wilson | OG | Concussion | — |
| NO | Nathan Shepherd | DT | Ankle | Questionable for start of Training Camp |
| NO | Chris Olave | WR | Illness | Questionable for start of Training Camp |
| NO | Alvin Kamara | RB | Knee - MCL | Questionable for start of Training Camp |
| NO | Spencer Rattler | QB | Finger | Questionable for start of Training Camp |
| NO | Bryan Bresee | DT | Knee | Questionable for start of Training Camp |
| NYG | Jevon Holland | SAF | Knee | Questionable for start of Training Camp |
| NYG | Jalin Hyatt | WR | Illness | Questionable for start of Training Camp |
| NYG | Theo Johnson | TE | Illness | Questionable for start of Training Camp |
| NYJ | Micheal Clemons | DE | Ankle | Questionable for start of Training Camp |
| NYJ | Breece Hall | RB | Knee | Questionable for start of Training Camp |
| NYJ | Brandon Stephens | CB | Neck | Questionable for start of Training Camp |
| NYJ | Jelani Woods | TE | Hamstring | Questionable for start of Training Camp |
| NYJ | Tyrod Taylor | QB | Knee | Questionable for start of Training Camp |
| NYJ | Qwan'tez Stiggers | CB | Knee | Questionable for start of Training Camp |
| PHI | Marcus Epps | SAF | Concussion | — |
| PHI | Dallas Goedert | TE | Knee | — |
| PHI | Lane Johnson | OT | Foot | Questionable for Wild Card vs San Francisco |
| PHI | Jalen Carter | DT | Hip | — |
| SEA | Charles Cross | OT | Hamstring | Questionable for Divisional Playoffs |
| SEA | Coby Bryant | SAF | Knee | Questionable for Divisional Playoffs |
| SF | Trent Williams | OT | Hamstring | Questionable for Wild Card at Philadelphia |
| SF | Luke Gifford | LB | Quadriceps | Questionable for Wild Card at Philadelphia |
| SF | Ricky Pearsall | WR | Knee - PCL | Questionable for Wild Card at Philadelphia |
| TB | Jamel Dean | CB | Shoulder | Questionable for start of Training Camp |
| TB | Anthony Nelson | LB | Knee | Questionable for start of Training Camp |
| TEN | James Williams | LB | Shoulder - AC Joint | Questionable for start of Training Camp |
| TEN | Cam Ward | QB | Shoulder - AC Joint | Questionable for start of Training Camp |
| TEN | Amani Hooker | SAF | Ankle | Questionable for start of Training Camp |
| TEN | Arden Key | LB | Hip | Questionable for start of Training Camp |
| TEN | Gunnar Helm | TE | Toe | Questionable for start of Training Camp |
| WAS | Laremy Tunsil | OT | Oblique | Questionable for start of Training Camp |
| WAS | Jayden Daniels | QB | Elbow | Questionable for start of Training Camp |
| WAS | Marcus Mariota | QB | Hand | Questionable for start of Training Camp |
| ARI | Simi Fehoko | WR | Wrist | IR. Injured Reserve |
| ARI | Channing Tindall | LB | Knee | Questionable for start of Training Camp |
| ARI | Mack Wilson | LB | Ribs | IR. Injured Reserve |
| ARI | Jonah Williams | OT | Shoulder | IR. Injured Reserve |
| ARI | Blake Gillikin | P | Back | IR. Injured Reserve |
| ARI | Will Hernandez | G | Hip | IR. Injured Reserve |
| ARI | Greg Dortch | WR | Chest | IR. Injured Reserve |
| ATL | C. Phillips III | CB | Triceps | IR. Injured Reserve |
| ATL | Cobee Bryant | CB | Concussion | Questionable for start of Training Camp |
| ATL | DeMarcco Hellams | SAF | Hamstring | IR. Injured Reserve |
| ATL | Sam Roberts | DE | Knee | IR. Injured Reserve |
| ATL | DeAngelo Malone | LB | Ankle | IR. Injured Reserve |
| BAL | Kyle Hamilton | SAF | Concussion | Questionable for start of Training Camp |
| BAL | Andrew Vorhees | OG | Foot | Questionable for start of Training Camp |
| BAL | Justice Hill | RB | Neck | IR. Injured Reserve |
| BAL | Broderick Washington | DT | Achilles | IR. Injured Reserve |
| BAL | Adisa Isaac | LB | Elbow | IR. Injured Reserve |
| BAL | Taven Bryan | DT | Knee | IR. Injured Reserve |
| CIN | Cam Taylor-Britt | CB | Foot | IR. Injured Reserve |
| CIN | DJ Turner | CB | Calf | Questionable for start of Training Camp |
| CIN | Matt Lee | C | Knee | IR. Injured Reserve |
| CIN | Brian Asamoah | LB | Knee | IR. Injured Reserve |
| CIN | Marco Wilson | CB | Hamstring | IR. Injured Reserve |
| CLE | DeAndre Carter | WR | Knee | IR. Injured Reserve |
| CLE | Denzel Ward | CB | Neck | Questionable for start of Training Camp |
| CLE | Luke Wypler | C | Knee | Questionable for start of Training Camp |
| CLE | Winston Reid | LB | Back | IR. Injured Reserve |
| CLE | Dom Jones | CB | Knee | IR. Injured Reserve |
| DAL | Markquese Bell | SAF | Concussion | Questionable for start of Training Camp |
| DAL | Ajani Cornelius | OT | Knee | IR. Injured Reserve |
| DAL | Payton Turner | DE | Ribs | IR. Injured Reserve |
| DAL | Trevor Keegan | G | Neck | IR. Injured Reserve |
| DAL | Jack Sanborn | LB | Groin | IR. Injured Reserve |
| DEN | Drew Sanders | LB | Foot | IR. Injured Reserve |
| DEN | Matt Peart | OT | Knee - MCL | IR. Injured Reserve |
| DEN | P.J. Locke | SAF | Leg | Questionable for Divisional Playoffs |
| DEN | Lucas Krull | TE | Foot | IR. Injured Reserve |
| DET | Zach Cunningham | ILB | Hamstring | IR. Injured Reserve |
| DET | Tom Kennedy | WR | Ribs | Questionable for start of Training Camp |
| DET | Giovanni Manu | OL | Knee | IR. Injured Reserve |
| DET | Brock Wright | TE | Neck | IR. Injured Reserve |
| DET | PortaSam LaPorta | TE | Back | IR. Injured Reserve |
| GB | Javon Bullard | SAF | Knee | — |
| HOU | Ajani Carter | DB | Hamstring | IR. Injured Reserve. Expected Return - Week 19 |
| HOU | Foley Fatukasi | DT | Shoulder | IR. Injured Reserve. Expected Return - Week 19 |
| IND | Cameron Mitchell | CB | Calf | Questionable for start of Training Camp |
| JAC | Cole Van Lanen | OG | Knee | Questionable for Wild Card vs Buffalo |
| KC | Josh Simmons | OT | Wrist | IR. Injured Reserve |
| KC | Jake Briningstool | TE | Hamstring | IR. Injured Reserve |
| KC | Ethan Driskell | OT | Appendix | NFI-R for start of Training Camp |
| KC | Christian Roland-Wallace | CB | Back | IR. Injured Reserve |
| LAC | Bud Dupree | OLB | Hamstring | Questionable for Wild Card at New England |
| LV | Brennan Jackson | LB | Foot | IR. Injured Reserve |
| LV | Jackson Powers-Johnson | G | Ankle | IR. Injured Reserve |
| LV | Isaiah Pola-Mao | SAF | Shoulder | Questionable for start of Training Camp |
| MIA | T. Wease Jr. | WR | Head | Questionable for start of Training Camp |
| MIA | Quinn Ewers | QB | Knee | Questionable for start of Training Camp |
| MIA | Jordan Colbert | SAF | Neck | IR. Injured Reserve |
| MIA | Jason Sanders | K | Hip | IR. Injured Reserve |
| MIA | Malik Washington | WR | Thumb | Questionable for start of Training Camp |
| MIN | Josh Oliver | TE | Ankle | Questionable for start of Training Camp |
| MIN | Jeff Okudah | CB | Concussion | IR. Injured Reserve |
| MIN | J.J. McCarthy | QB | Hand | Questionable for start of Training Camp |
| NO | Vernon Broughton | DT | Hip | IR. Injured Reserve |
| NO | K. Banks Jr. | OT | Ankle | Questionable for start of Training Camp |
| NO | Trey Palmer | WR | Ankle | IR. Injured Reserve |
| NYG | Darius Muasau | LB | Ankle | Questionable for start of Training Camp |
| NYG | T. Fidone II | TE | Foot | IR. Injured Reserve |
| NYG | Rico Payton | CB | Head | Questionable for start of Training Camp |
| NYG | Micah McFadden | LB | Foot | IR. Injured Reserve |
| NYG | Evan Neal | OT | Neck | IR. Injured Reserve |
| NYG | Chris Board | LB | Chest | IR. Injured Reserve |
| NYJ | Josh Reynolds | WR | Hip | IR. Injured Reserve |
| NYJ | J. Brownlee Jr. | CB | Hip | IR. Injured Reserve |
| NYJ | Braelon Allen | RB | Knee - MCL | IR. Injured Reserve |
| NYJ | Marcelino McCrary-Ball | LB | Hamstring | IR. Injured Reserve |
| NYJ | Quincy Williams | LB | Hand | Questionable for start of Training Camp |
| PHI | Andrew Mukuba | SAF | Ankle | IR. Injured Reserve. Expected Return - Week 19 |
| PHI | Grant Calcaterra | TE | Ankle | — |
| PHI | SumerenBen VanSumeren | RB | Knee | IR. Injured Reserve. Expected Return - Week 19 |
| PIT | Skylar Thompson | QB | Hamstring | IR. Injured Reserve. Expected Return - Week 19 |
| PIT | Calvin Anderson | OT | Knee | IR. Injured Reserve. Expected Return - Week 19 |
| PIT | DeShon Elliott | SAF | Knee | IR. Injured Reserve. Expected Return - Week 19 |
| SF | Dee Winters | LB | Ankle | Questionable for Wild Card at Philadelphia |
| TB | Anthony Walker | MLB | Ankle | Questionable for start of Training Camp |
| TB | Ben Bredeson | G | Knee | IR. Injured Reserve |
| TB | Zyon McCollum | CB | Hip | IR. Injured Reserve |
| TEN | Corey Levin | OG | Biceps | Questionable for start of Training Camp |
| TEN | Kevin Zeitler | OG | Quadriceps | Questionable for start of Training Camp |
| TEN | L'Jarius Sneed | CB | Quadriceps | IR. Injured Reserve |
| TEN | Blake Hance | OL | Shoulder | IR. Injured Reserve |
| CLE | Carson Schwesinger | LB | Ankle | IR. Injured Reserve |
| DAL | Javonte Williams | RB | Shoulder | IR. Injured Reserve |
| DAL | Malik Davis | RB | Eye | IR. Injured Reserve |
| DAL | T.J. Bass | G | Knee | IR. Injured Reserve |
| DET | Trystan Colon-Castillo | C | Wrist | IR. Injured Reserve |
| GB | Donovan Jennings | OT | Neck | IR. Injured Reserve |
| GB | Savion Williams | WR | Foot | IR. Injured Reserve |
| LAC | Nikko Reed | CB | Hamstring | IR. Injured Reserve |
| NYG | Wan'Dale Robinson | WR | Ribs | IR. Injured Reserve |
| NYG | Cordale Flott | CB | Knee | IR. Injured Reserve |
| NYG | Rakeem Nunez-Roches | DT | Ankle | IR. Injured Reserve |
| NYJ | Isaiah Davis | RB | Concussion | IR. Injured Reserve |
| NYJ | Xavier Newman-Johnson | G | Knee | IR. Injured Reserve |
| NYJ | Mason Taylor | TE | Neck | IR. Injured Reserve |
| SEA | George Holani | RB | Hamstring | IR. Injured Reserve |
| SEA | Tory Horton | WR | Shin | IR. Injured Reserve |
| SEA | Chazz Surratt | LB | Ankle | IR. Injured Reserve |
| TEN | Van Jefferson | WR | Forearm | IR. Injured Reserve |
| TEN | Jalyn Armour-Davis | CB | Achilles | IR. Injured Reserve |
| ARI | M. Harrison Jr. | WR | Foot | IR. Injured Reserve |
| IND | Daniel Scott | SAF | Knee | IR. Injured Reserve |
| MIA | Darren Waller | TE | Groin | IR. Injured Reserve |
| NO | Mason Tipton | WR | Groin | IR. Injured Reserve |
| NO | Jack Stoll | TE | Knee | IR. Injured Reserve |
| NO | Michael Davis | CB | Shoulder | IR. Injured Reserve |
| NO | Zaire Mitchell-Paden | TE | Knee | IR. Injured Reserve |
| TEN | Oluwafemi Oladejo | LB | Lower Leg | IR. Injured Reserve |
| ARI | Kitan Crawford | SAF | Ankle | IR. Injured Reserve |
| ATL | Mike Hughes | CB | Ankle | IR. Injured Reserve |
| CAR | Ja'Tavion Sanders | TE | Lower Leg | IR. Injured Reserve |
| CHI | Noah Sewell | LB | Achilles | IR. Injured Reserve |
| CLE | Wyatt Teller | G | Calf | IR. Injured Reserve |
| GB | Nate Hobbs | CB | Knee | IR. Injured Reserve |
| GB | Zayne Anderson | SAF | Ankle | IR. Injured Reserve |
| IND | Anthony Richardson | QB | Eye | IR. Injured Reserve |
| LV | Kolton Miller | OT | Ankle | IR. Injured Reserve |
| NYG | Joshua Ezeudu | G | Calf | IR. Injured Reserve |
| NYG | Beaux Collins | WR | Concussion | IR. Injured Reserve |
| PIT | Darnell Washington | TE | Forearm | IR. Injured Reserve |
| WAS | Tyler Biadasz | C | Knee | IR. Injured Reserve |
| ARI | Kei'Trel Clark | CB | Back | IR. Injured Reserve |
| GB | Jordon Riley | DT | Achilles | IR. Injured Reserve |
| GB | Kamal Hadden | CB | Ankle | IR. Injured Reserve |
| IND | Anthony Gould | WR | Foot | IR. Injured Reserve |
| IND | Braden Smith | OT | Concussion | IR. Injured Reserve |
| IND | Chris Lammons | DB | Foot | IR. Injured Reserve |
| IND | Andrew Ogletree | TE | Neck | IR. Injured Reserve |
| IND | Charvarius Ward | CB | Concussion | IR. Injured Reserve |
| IND | DeForest Buckner | DT | Neck | IR. Injured Reserve |
| SEA | Cody White | WR | Groin | IR. Injured Reserve |
| MIN | Elijah Williams | DE | Ankle | IR. Injured Reserve |
| SF | Kurtis Rourke | QB | Knee | NFI-R for Wild Card at Philadelphia |
| LV | Brock Bowers | TE | Knee - PCL | IR. Injured Reserve |
| MIA | Caleb Johnson | LB | Shoulder | IR. Injured Reserve |
| ARI | P. Johnson Jr. | OT | Knee - MCL | IR. Injured Reserve |
| CAR | Trevin Wallace | LB | Shoulder | IR. Injured Reserve |
| LV | Maxx Crosby | DE | Knee | IR. Injured Reserve |
| MIA | Isaiah Johnson | CB | Knee | IR. Injured Reserve |
| MIA | D'Wayne Eskridge | WR | Toe | IR. Injured Reserve |
| MIA | Benito Jones | DT | Back | IR. Injured Reserve |
| NE | Mack Hollins | WR | Abdomen | IR. Injured Reserve |
| NYG | Andrew Thomas | OT | Hamstring | IR. Injured Reserve |
| NYG | Tyler Nubin | SAF | Neck | IR. Injured Reserve |
| NYG | John Michael Schmitz | C | Finger | IR. Injured Reserve |
| NYG | D.J. Davidson | DT | Neck | IR. Injured Reserve |
| SF | Fred Warner | MLB | Ankle | IR. Injured Reserve |
| TEN | Marcus Harris | CB | Knee | IR. Injured Reserve |
| DET | Kerby Joseph | SAF | Knee | IR. Injured Reserve |
| GB | Kristian Welch | LB | Ankle | IR. Injured Reserve |
| NO | Foster Moreau | TE | Ankle | IR. Injured Reserve |
| NYJ | Francisco Mauigoa | LB | Neck | IR. Injured Reserve |
| NYJ | W. McDonald IVWill McDonald IV | DE | Knee | IR. Injured Reserve |
| NYJ | Jay Tufele | DT | Foot | IR. Injured Reserve |
| DEN | Luke Wattenberg | C | Shoulder | IR. Injured Reserve |
| HOU | Jake Hansen | LB | Chest | IR. Injured Reserve |
| JAC | Jourdan Lewis | CB | Foot | IR. Injured Reserve |
| KC | Nikko Remigio | WR | Knee | IR. Injured Reserve |
| CLE | Quinshon Judkins | RB | Ankle | IR. Injured Reserve |
| DAL | Tyler Guyton | OT | Ankle | IR. Injured Reserve |
| KC | Tyquan Thornton | WR | Concussion | IR. Injured Reserve |
| KC | Trent McDuffie | CB | Knee | IR. Injured Reserve |
| KC | Jaylen Watson | CB | Groin | IR. Injured Reserve |
| KC | Rashee Rice | WR | Concussion | IR. Injured Reserve |
| LV | Jeremy Chinn | SAF | Back | IR. Injured Reserve |
| MIN | Ryan Kelly | C | Concussion | IR. Injured Reserve |
| NYJ | Justin Fields | QB | Knee | IR. Injured Reserve |
| ARI | Garrett Williams | CB | Achilles | IR. Injured Reserve |
| ARI | Walter Nolen | DT | Knee | IR. Injured Reserve |
| CAR | Popo Aumavae | DT | Achilles | IR. Injured Reserve |
| NE | Joshua Farmer | DT | Hamstring | IR. Injured Reserve |
| GB | PatrickJohn FitzPatrick | TE | Achilles | IR. Injured Reserve |
| KC | Gardner Minshew | QB | Knee | IR. Injured Reserve |
| LV | Jordan Meredith | C | Ankle | IR. Injured Reserve |
| MIA | James Daniels | G | Pectoral | IR. Injured Reserve |
| WAS | Eddie Goldman | NT | Concussion | IR. Injured Reserve |
| WAS | Samuel Cosmi | G | Concussion | IR. Injured Reserve |
| WAS | Jaylin Lane | WR | Ankle | IR. Injured Reserve |
| DAL | DaRon Bland | CB | Foot | IR. Injured Reserve |
| SF | Nick Martin | LB | Concussion | IR. Injured Reserve |
| BAL | Teddye Buchanan | LB | Knee - ACL | IR. Injured Reserve |
| CLE | Jack Conklin | OT | Concussion | IR. Injured Reserve |
| KC | Jawaan Taylor | OT | Elbow | IR. Injured Reserve |
| KC | Leo Chenal | LB | Shoulder | IR. Injured Reserve |
| MIA | Elijah Campbell | DB | Ankle | IR. Injured Reserve |
| NYG | Kayvon Thibodeaux | LB | Shoulder | IR. Injured Reserve |
| ATL | Khadarel Hodge | WR | Shoulder | IR. Injured Reserve |
| BUF | Chase Lundt | OT | Knee | IR. Injured Reserve |
| CIN | Kris Jenkins | DT | Ankle | IR. Injured Reserve |
| DAL | Juanyeh Thomas | SAF | Migraine | NFI-R for start of Training Camp |
| GB | MarShawn Lloyd | RB | Hamstring | IR. Injured Reserve |
| MIN | Christian Darrisaw | OT | Knee | IR. Injured Reserve |
| NO | Devaughn Vele | WR | Shoulder | IR. Injured Reserve |
| NYJ | Garrett Wilson | WR | Knee | IR. Injured Reserve |
| NO | Devin Neal | RB | Hamstring | IR. Injured Reserve |
| NYJ | Tony Adams | SAF | Groin | IR. Injured Reserve |
| ATL | Bralen Trice | LB | Knee | IR. Injured Reserve |
| ATL | Zach Harrison | DE | Knee | IR. Injured Reserve |
| GB | Micah Parsons | DE | Knee - ACL | IR. Injured Reserve |
| KC | Patrick Mahomes | QB | Knee - ACL | IR. Injured Reserve |
| MIN | Jonathan Greenard | LB | Shoulder | IR. Injured Reserve |
| MIN | Josh Metellus | SAF | Shoulder | IR. Injured Reserve |
| ARI | Andre Baccellia | WR | Neck | IR. Injured Reserve |
| ARI | Zonovan Knight | RB | Ankle | IR. Injured Reserve |
| JAC | Jack Kiser | LB | Undisclosed | IR. Injured Reserve |
| TEN | K. Winston Jr. | SAF | Hamstring | IR. Injured Reserve |
| TEN | Xavier Woods | FS | Hamstring | IR. Injured Reserve |
| TEN | Mike Brown | SAF | Ankle | IR. Injured Reserve |
| WAS | Javontae Jean-Baptiste | DE | Pectoral | IR. Injured Reserve |
| WAS | Trey Amos | CB | Lower Leg | IR. Injured Reserve |
| WAS | Noah Brown | WR | Ribs | IR. Injured Reserve |
| WAS | Luke McCaffrey | WR | Collarbone | IR. Injured Reserve |
| DEN | Brandon Jones | SAF | Pectoral | IR. Injured Reserve |
| HOU | Mario Edwards | DT | Pectoral | IR. Injured Reserve |
| NYJ | Isaiah Oliver | SAF | Knee | IR. Injured Reserve |
| ARI | Bilal Nichols | DT | Knee | IR. Injured Reserve |
| DET | Brian Branch | SAF | Achilles | IR. Injured Reserve |
| HOU | Jaylin Smith | CB | Undisclosed | IR. Injured Reserve |
| KC | Wanya Morris | OT | Knee | IR. Injured Reserve |
| NYG | Nic Jones | CB | Shoulder | IR. Injured Reserve |
| NYG | Victor Dimukeje | LB | Knee | IR. Injured Reserve |
| NYJ | Azareye'h Thomas | CB | Shoulder | IR. Injured Reserve |
| CIN | Trey Hendrickson | DE | Pelvis | IR. Injured Reserve |
| ARI | Trey Benson | RB | Knee - Meniscus | IR. Injured Reserve |
| NYJ | Tyler Baron | DE | Knee | IR. Injured Reserve |
| PHI | Myles Hinton | OT | Back | IR. Injured Reserve |
| WAS | Zach Ertz | TE | Knee - ACL | IR. Injured Reserve |
| CLE | Jerome Ford | RB | Shoulder | IR. Injured Reserve |
| CLE | Ethan Pocic | C | Achilles | IR. Injured Reserve |
| IND | Daniel Jones | QB | Achilles | IR. Injured Reserve |
| LV | Kyu Blu Kelly | CB | Knee | IR. Injured Reserve |
| ARI | Kyler Murray | QB | Foot | IR. Injured Reserve |
| GB | Devonte Wyatt | DT | Ankle | IR. Injured Reserve |
| PIT | Donte Kent | CB | Ankle | IR. Injured Reserve |
| HOU | Tim Settle | DT | Foot | IR. Injured Reserve |
| ATL | Malik Verdon | LB | Shoulder | NFI-R for start of Training Camp |
| CLE | Maliek Collins | DT | Quadriceps | IR. Injured Reserve |
| BUF | Tyler Bass | K | Hip | IR. Injured Reserve |
| DET | Terrion Arnold | CB | Shoulder | IR. Injured Reserve |
| PIT | Broderick Jones | OT | Neck | IR. Injured Reserve |
| DET | Josh Paschal | DE | Back | NFI-R for start of Training Camp |
| PHI | Willie Lampkin | G | Knee | IR. Injured Reserve |
| CAR | Corey Thornton | CB | Lower Leg | IR. Injured Reserve |
| ATL | B. Bowman Jr. | SAF | Achilles | IR. Injured Reserve |
| HOU | Joe Mixon | RB | Foot | NFI-R for Wild Card at Pittsburgh |
| PIT | Cory Trice | CB | Knee | IR. Injured Reserve |
| ATL | M. Penix Jr. | QB | Knee - ACL | IR. Injured Reserve |
| MIA | Julius Brents | CB | Foot | IR. Injured Reserve |
| NYJ | Kris Boyd | CB | Abdomen | IR. Injured Reserve |
| TEN | Calvin Ridley | WR | Lower Leg | IR. Injured Reserve |
| DEN | J.K. Dobbins | RB | Foot | IR. Injured Reserve |
| ARI | Zay Jones | WR | Achilles | IR. Injured Reserve |
| ATL | Storm Norton | OT | Foot | IR. Injured Reserve |
| HOU | M.J. Stewart | SAF | Quadriceps | IR. Injured Reserve |
| NYG | Graham Gano | K | Neck | IR. Injured Reserve |
| JAC | Travis Hunter | WR | Knee | IR. Injured Reserve |
| SF | Mykel Williams | DE | Knee - ACL | IR. Injured Reserve |
| LAC | Joe Alt | OT | Ankle | IR. Injured Reserve |
| NYJ | Andre Cisco | SAF | Pectoral | IR. Injured Reserve |
| CHI | Dayo Odeyingbo | DE | Achilles | IR. Injured Reserve |
| GB | Tucker Kraft | TE | Knee - ACL | IR. Injured Reserve |
| WAS | Marshon Lattimore | CB | Knee - ACL | IR. Injured Reserve |
| BUF | Mike Hoecht | LB | Achilles | IR. Injured Reserve |
| PIT | Daniel Ekuale | DT | Knee - ACL | IR. Injured Reserve |
| CAR | Brady Christensen | OT | Achilles | IR. Injured Reserve |
| CHI | Shemar Turner | DT | Knee - ACL | IR. Injured Reserve |
| MIA | Storm Duck | CB | Knee | IR. Injured Reserve |
| NYG | Cam Skattebo | RB | Ankle | IR. Injured Reserve |
| MIN | Carson Wentz | QB | Shoulder | IR. Injured Reserve |
| CHI | Zah Frazier | CB | Personal | NFI-R for Wild Card vs Green Bay |
| LAC | Josh Fuga | DT | Undisclosed | IR. Injured Reserve |
| NO | Julian Blackmon | SAF | Shoulder - Labrum | IR. Injured Reserve |
| KC | Omarr Norman-Lott | DT | Knee - ACL | IR. Injured Reserve |
| NO | Erik McCoy | C | Biceps | IR. Injured Reserve |
| NO | Kendre Miller | RB | Knee - ACL | IR. Injured Reserve |
| PIT | Miles Killebrew | SAF | Knee | IR. Injured Reserve |
| WAS | Dorance Armstrong | DE | Knee | IR. Injured Reserve |
| CAR | P. Jones II | LB | Back | IR. Injured Reserve |
| SF | Tarron Jackson | DE | Undisclosed | IR. Injured Reserve |
| ARI | Travis Vokolek | TE | Neck | IR. Injured Reserve |
| DET | Colby Sorsdal | G | Leg | IR. Injured Reserve |
| DET | Jamarco Jones | OT | Achilles | IR. Injured Reserve |
| IND | Salvon Ahmed | RB | Ankle | IR. Injured Reserve |
| DAL | Miles Sanders | RB | Knee | IR. Injured Reserve |
| NE | Antonio Gibson | RB | Knee - ACL | IR. Injured Reserve |
| ARI | Tip Reiman | TE | Ankle | IR. Injured Reserve |
| IND | Spencer Shrader | K | Knee - ACL + MCL | IR. Injured Reserve |
| NYG | Malik Nabers | WR | Knee - ACL | IR. Injured Reserve |
| ARI | Joey Blount | SAF | Neck | IR. Injured Reserve |
| ARI | S. Thomas V | CB | Knee - ACL | IR. Injured Reserve |
| ARI | Sean Murphy-Bunting | CB | Knee | NFI-R for start of Training Camp |
| ARI | Valentin Senn | OT | Undisclosed | IR. Injured Reserve |
| ARI | JJ Russell | ILB | Concussion | IR. Injured Reserve |
| ATL | Emory Jones | QB | Concussion | IR. Injured Reserve |
| ATL | Kaleb McGary | OT | Leg | IR. Injured Reserve |
| ATL | T. Wheatley Jr. | OT | Undisclosed | IR. Injured Reserve |
| BAL | Robert Longerbeam | CB | Knee | IR. Injured Reserve |
| BAL | Bilhal Kone | CB | Knee | IR. Injured Reserve |
| BAL | Dayton Wade | WR | Ribs | IR. Injured Reserve |
| BUF | Wande Owens | SAF | Undisclosed | IR. Injured Reserve |
| CHI | Terell Smith | CB | Knee | IR. Injured Reserve |
| CHI | Deion Hankins | RB | Quadriceps | IR. Injured Reserve |
| CIN | Cordell Volson | G | Shoulder | IR. Injured Reserve |
| CLE | Nathaniel Watson | LB | Biceps | IR. Injured Reserve |
| CLE | Martin Emerson | CB | Achilles | IR. Injured Reserve |
| CLE | Justin Osborne | C | Undisclosed | IR. Injured Reserve |
| CLE | Dawand Jones | OT | Knee | IR. Injured Reserve |
| CLE | Anthony Kendall | CB | Undisclosed | IR. Injured Reserve |
| DAL | Robert Jones | G | Neck | IR. Injured Reserve |
| DEN | J. Walker Jr. | LB | Undisclosed | IR. Injured Reserve |
| DEN | Michael Burton | FB | Hamstring | IR. Injured Reserve |
| DEN | Nick Gargiulo | G | Knee | IR. Injured Reserve |
| DEN | Matt Henningsen | DE | Achilles | IR. Injured Reserve |
| DET | Kye Robichaux | RB | Undisclosed | IR. Injured Reserve |
| DET | E. Rakestraw Jr. | CB | Shoulder | IR. Injured Reserve |
| DET | Dan Jackson | SAF | Leg | IR. Injured Reserve |
| DET | Zeke Turner | LB | Foot | IR. Injured Reserve |
| GB | Travis Glover | OT | Shoulder | IR. Injured Reserve |
| HOU | Kyonte Hamilton | DT | Ankle | IR. Injured Reserve |
| HOU | Brevin Jordan | TE | Knee | IR. Injured Reserve |
| IND | Jack Wilson | OT | Undisclosed | IR. Injured Reserve |
| IND | Justin Walley | CB | Knee - ACL | IR. Injured Reserve |
| IND | Blake Freeland | OT | Leg | IR. Injured Reserve |
| IND | Jacob Phillips | LB | Biceps | IR. Injured Reserve |
| IND | D.J. Montgomery | WR | Undisclosed | IR. Injured Reserve |
| IND | Hunter Wohler | SAF | Foot | IR. Injured Reserve |
| JAC | Joshua Cephus | WR | Undisclosed | IR. Injured Reserve |
| JAC | Caleb Ransaw | CB | Lower Body | IR. Injured Reserve |
| KC | Keaontay Ingram | RB | Undisclosed | IR. Injured Reserve |
| KC | Janarius Robinson | DE | Foot | IR. Injured Reserve |
| KC | E. Scott, Jr. | CB | Undisclosed | IR. Injured Reserve |
| KC | Brandon George | LB | Undisclosed | IR. Injured Reserve |
| KC | Deon Bush | SAF | Achilles | IR. Injured Reserve |
| KC | Felix Anudike-Uzomah | DE | Hamstring | IR. Injured Reserve |
| LAC | Rashawn Slater | OT | Kneecap | IR. Injured Reserve |
| LAC | Najee Harris | RB | Achilles | IR. Injured Reserve |
| LAC | Jordan Oladokun | CB | Undisclosed | IR. Injured Reserve |
| LAC | Junior Colson | LB | Shoulder | IR. Injured Reserve |
| LAR | Keir Thomas | LB | Undisclosed | IR. Injured Reserve |
| MIA | Jason Maitre | DB | Undisclosed | IR. Injured Reserve |
| MIA | Alexander Mattison | RB | Neck | IR. Injured Reserve |
| MIA | Jalin Conyers | TE | Leg | IR. Injured Reserve |
| MIA | Kader Kohou | CB | Knee - ACL | IR. Injured Reserve |
| MIA | Germain Ifedi | OT | Undisclosed | IR. Injured Reserve |
| MIA | Artie Burns | CB | Knee - ACL | IR. Injured Reserve |
| MIA | Tyreek Hill | WR | Knee - ACL | IR. Injured Reserve |
| MIA | Yodny Cajuste | OT | Undisclosed | IR. Injured Reserve |
| MIA | Obinna Eze | OT | Undisclosed | IR. Injured Reserve |
| MIN | Rondale Moore | WR | Knee | IR. Injured Reserve |
| MIN | Zeke Correll | C | Ankle | IR. Injured Reserve |
| MIN | Matt Nelson | OT | Undisclosed | IR. Injured Reserve |
| NE | Deneric Prince | RB | Undisclosed | IR. Injured Reserve |
| NE | Yasir Durant | OT | Undisclosed | IR. Injured Reserve |
| NE | Jaquelin Roy | DT | Undisclosed | IR. Injured Reserve |
| NE | Brock Lampe | RB | Undisclosed | IR. Injured Reserve |
| NE | Marcellas Dial | CB | Knee - ACL | IR. Injured Reserve |
| NE | Lan Larison | RB | Foot | IR. Injured Reserve |
| NE | Isaiah Iton | DT | Hip | IR. Injured Reserve |
| NO | Bub Means | WR | Lower Leg | IR. Injured Reserve |
| NO | Landon Young | OT | Ankle | IR. Injured Reserve |
| NO | Mason Pline | TE | Upper Body | IR. Injured Reserve |
| NO | Ja'Lynn Polk | WR | Shoulder | IR. Injured Reserve |
| NO | Will Clapp | C | Foot | IR. Injured Reserve |
| NYG | TJ Moore | CB | Upper Leg | IR. Injured Reserve |
| NYG | Bryce Ford-Wheaton | WR | Achilles | IR. Injured Reserve |
| NYG | Da'Quan Felton | WR | Undisclosed | IR. Injured Reserve |
| NYJ | Gus Hartwig | C | Undisclosed | IR. Injured Reserve |
| PHI | Obo Okoronkwo | DE | Triceps | IR. Injured Reserve |
| PHI | Johnny Wilson | WR | Knee | IR. Injured Reserve |
| PIT | Dean Lowry | DT | Knee | IR. Injured Reserve |
| PIT | Jacob Slade | DT | Undisclosed | IR. Injured Reserve |
| PIT | D. Parham Jr. | TE | Achilles | IR. Injured Reserve |
| SEA | AJ Finley | SAF | Knee | IR. Injured Reserve |
| SEA | Kenny McIntosh | RB | Knee - ACL | IR. Injured Reserve |
| SF | Trent Taylor | WR | Undisclosed | IR. Injured Reserve |
| SF | Jakob Robinson | CB | Forearm | IR. Injured Reserve |
| SF | Patrick Taylor | RB | Shoulder | IR. Injured Reserve |
| SF | Tre'Vius Hodges-Tomlinson | CB | Undisclosed | IR. Injured Reserve |
| TB | J.J. Roberts | SAF | Knee | IR. Injured Reserve |
| TB | David Walker | LB | Knee | IR. Injured Reserve |
| TB | Ko Kieft | TE | Leg | IR. Injured Reserve |
| TB | Jaden Smith | WR | Undisclosed | IR. Injured Reserve |
| TEN | Anfernee Orji | LB | Knee - ACL | IR. Injured Reserve |
| TEN | Will Levis | QB | Shoulder | IR. Injured Reserve |
| WAS | Lucas Niang | OT | Knee - ACL | IR. Injured Reserve |
| WAS | Tyree Jackson | TE | Undisclosed | IR. Injured Reserve |
| BAL | Nnamdi Madubuike | DT | Neck | IR. Injured Reserve |
| SF | Nick Bosa | DE | Knee - ACL | IR. Injured Reserve |
| ARI | James Conner | RB | Foot | IR. Injured Reserve |
| PIT | Max Scharping | G | Knee | IR. Injured Reserve |
| TB | Cody Mauch | G | Knee | IR. Injured Reserve |
| WAS | D. Wise Jr. | DE | Quadriceps | IR. Injured Reserve |
| WAS | Austin Ekeler | RB | Achilles | IR. Injured Reserve |
| CAR | Damarri Mathis | DB | Knee - ACL | IR. Injured Reserve |
| NYJ | Alijah Vera-Tucker | G | Triceps | IR. Injured Reserve |
| BUF | DeWayne Carter | DT | Achilles | IR. Injured Reserve |
| NO | Nick Saldiveri | G | Knee | IR. Injured Reserve |
| Player | Pos | Injury | Status | |
|---|---|---|---|---|
| ARI | Trey Benson | RB | Knee - Meniscus | IR. Injured Reserve |
| ARI | Kyler Murray | QB | Foot | IR. Injured Reserve |
| ARI | Zay Jones | WR | Achilles | IR. Injured Reserve |
| ARI | Travis Vokolek | TE | Neck | IR. Injured Reserve |
| ARI | Tip Reiman | TE | Ankle | IR. Injured Reserve |
| ARI | Joey Blount | SAF | Neck | IR. Injured Reserve |
| ARI | S. Thomas V | CB | Knee - ACL | IR. Injured Reserve |
| ARI | Sean Murphy-Bunting | CB | Knee | NFI-R for start of Training Camp |
| ARI | Valentin Senn | OT | Undisclosed | IR. Injured Reserve |
| ARI | JJ Russell | ILB | Concussion | IR. Injured Reserve |
| ARI | James Conner | RB | Foot | IR. Injured Reserve |
| ARI | Evan Brown | OG | Personal | Questionable for start of Training Camp |
| ARI | Simi Fehoko | WR | Wrist | IR. Injured Reserve |
| ARI | Channing Tindall | LB | Knee | Questionable for start of Training Camp |
| ARI | Mack Wilson | LB | Ribs | IR. Injured Reserve |
| ARI | Jonah Williams | OT | Shoulder | IR. Injured Reserve |
| ARI | Blake Gillikin | P | Back | IR. Injured Reserve |
| ARI | Will Hernandez | G | Hip | IR. Injured Reserve |
| ARI | Greg Dortch | WR | Chest | IR. Injured Reserve |
| ARI | M. Harrison Jr. | WR | Foot | IR. Injured Reserve |
| ARI | Kitan Crawford | SAF | Ankle | IR. Injured Reserve |
| ARI | Kei'Trel Clark | CB | Back | IR. Injured Reserve |
| ARI | P. Johnson Jr. | OT | Knee - MCL | IR. Injured Reserve |
| ARI | Garrett Williams | CB | Achilles | IR. Injured Reserve |
| ARI | Walter Nolen | DT | Knee | IR. Injured Reserve |
| ARI | Andre Baccellia | WR | Neck | IR. Injured Reserve |
| ARI | Zonovan Knight | RB | Ankle | IR. Injured Reserve |
| ARI | Bilal Nichols | DT | Knee | IR. Injured Reserve |
| ATL | Mike Hughes | CB | Ankle | IR. Injured Reserve |
| ATL | Khadarel Hodge | WR | Shoulder | IR. Injured Reserve |
| ATL | Bralen Trice | LB | Knee | IR. Injured Reserve |
| ATL | Zach Harrison | DE | Knee | IR. Injured Reserve |
| ATL | Malik Verdon | LB | Shoulder | NFI-R for start of Training Camp |
| ATL | B. Bowman Jr. | SAF | Achilles | IR. Injured Reserve |
| ATL | M. Penix Jr. | QB | Knee - ACL | IR. Injured Reserve |
| ATL | Storm Norton | OT | Foot | IR. Injured Reserve |
| ATL | Emory Jones | QB | Concussion | IR. Injured Reserve |
| ATL | Kaleb McGary | OT | Leg | IR. Injured Reserve |
| ATL | T. Wheatley Jr. | OT | Undisclosed | IR. Injured Reserve |
| ATL | Troy Andersen | LB | Knee | Physically Unable to Perform |
| ATL | Ronnie Harrison | LB | Illness | Questionable for start of Training Camp |
| ATL | Brandon Dorlus | DE | Hamstring | Questionable for start of Training Camp |
| ATL | C. Phillips III | CB | Triceps | IR. Injured Reserve |
| ATL | Cobee Bryant | CB | Concussion | Questionable for start of Training Camp |
| ATL | DeMarcco Hellams | SAF | Hamstring | IR. Injured Reserve |
| ATL | Sam Roberts | DE | Knee | IR. Injured Reserve |
| ATL | DeAngelo Malone | LB | Ankle | IR. Injured Reserve |
| BAL | Rashod Bateman | WR | Illness | Questionable for start of Training Camp |
| BAL | Kyle Hamilton | SAF | Concussion | Questionable for start of Training Camp |
| BAL | Andrew Vorhees | OG | Foot | Questionable for start of Training Camp |
| BAL | Justice Hill | RB | Neck | IR. Injured Reserve |
| BAL | Broderick Washington | DT | Achilles | IR. Injured Reserve |
| BAL | Adisa Isaac | LB | Elbow | IR. Injured Reserve |
| BAL | Taven Bryan | DT | Knee | IR. Injured Reserve |
| BAL | Teddye Buchanan | LB | Knee - ACL | IR. Injured Reserve |
| BAL | Robert Longerbeam | CB | Knee | IR. Injured Reserve |
| BAL | Bilhal Kone | CB | Knee | IR. Injured Reserve |
| BAL | Dayton Wade | WR | Ribs | IR. Injured Reserve |
| BAL | Nnamdi Madubuike | DT | Neck | IR. Injured Reserve |
| BUF | Tyler Bass | K | Hip | IR. Injured Reserve |
| BUF | Mike Hoecht | LB | Achilles | IR. Injured Reserve |
| BUF | Wande Owens | SAF | Undisclosed | IR. Injured Reserve |
| BUF | DeWayne Carter | DT | Achilles | IR. Injured Reserve |
| BUF | Josh Palmer | WR | Ankle | IR. Injured Reserve |
| BUF | Matt Prater | K | Quadriceps | Questionable for Wild Card at Jacksonville |
| BUF | Damar Hamlin | SAF | Pectoral | IR. Injured Reserve |
| BUF | Terrel Bernard | LB | Calf | Out for Wild Card at Jacksonville |
| BUF | Jordan Phillips | DT | Ankle | IR. Injured Reserve |
| BUF | Shaq Green-Thompson | OLB | Neck | Questionable for Wild Card at Jacksonville |
| BUF | Dalton Kincaid | TE | Knee | — |
| BUF | Landon Jackson | DE | Knee | IR. Injured Reserve |
| BUF | Dorian Strong | CB | Neck | IR. Injured Reserve |
| BUF | Ed Oliver | DT | Knee - Meniscus | IR. Injured Reserve |
| BUF | DaQuan Jones | DT | Calf | — |
| BUF | Taylor Rapp | SAF | Knee | IR. Injured Reserve |
| BUF | Jordan Poyer | FS | Hamstring | — |
| BUF | Maxwell Hairston | CB | Ankle | Out for Wild Card at Jacksonville |
| BUF | Curtis Samuel | WR | Elbow | IR. Injured Reserve |
| BUF | Ty Johnson | RB | Ankle | Questionable for Wild Card at Jacksonville |
| BUF | Chase Lundt | OT | Knee | IR. Injured Reserve |
| CAR | Ja'Tavion Sanders | TE | Lower Leg | IR. Injured Reserve |
| CAR | Trevin Wallace | LB | Shoulder | IR. Injured Reserve |
| CAR | Popo Aumavae | DT | Achilles | IR. Injured Reserve |
| CAR | Corey Thornton | CB | Lower Leg | IR. Injured Reserve |
| CAR | Brady Christensen | OT | Achilles | IR. Injured Reserve |
| CAR | P. Jones II | LB | Back | IR. Injured Reserve |
| CAR | Damarri Mathis | DB | Knee - ACL | IR. Injured Reserve |
| CAR | Jaycee Horn | CB | Head | Questionable for Wild Card vs L.A. Rams |
| CAR | Krys Barnes | LB | Coach's Decision | Inactive for Wild Card vs L.A. Rams |
| CAR | Ikem Ekwonu | OT | Knee | Questionable for Wild Card vs L.A. Rams |
| CAR | Robert Hunt | OT | Pectoral | Questionable for Wild Card vs L.A. Rams |
| CAR | Nick Samac | C | Coach's Decision | Inactive for Wild Card vs L.A. Rams |
| CAR | Tershawn Wharton | DE | Hamstring | Questionable for Wild Card vs L.A. Rams |
| CAR | LaBryan Ray | DT | Coach's Decision | Inactive for Wild Card vs L.A. Rams |
| CAR | Chandler Zavala | G | Calf | IR. Injured Reserve |
| CAR | Jared Harrison-Hunte | DE | Coach's Decision | Inactive for Wild Card vs L.A. Rams |
| CAR | Jonathon Brooks | RB | Knee - ACL | Physically Unable to Perform |
| CHI | T.J. Edwards | LB | Lower Leg | Out for Wild Card vs Green Bay |
| CHI | Andrew Billings | DT | Hip | Questionable for Wild Card vs Green Bay |
| CHI | Ozzy Trapilo | OT | Knee | Out for Wild Card vs Green Bay |
| CHI | Case Keenum | QB | Coach's Decision | Inactive for Wild Card vs Green Bay |
| CHI | Amen Ogbongbemiga | LB | Concussion | Inactive for Wild Card vs Green Bay |
| CHI | Chauncey Gardner-Johnson | SAF | Concussion | Inactive for Wild Card vs Green Bay |
| CHI | Luke Newman | G | Coach's Decision | Inactive for Wild Card vs Green Bay |
| CHI | Kyler Gordon | CB | Groin | Questionable for Wild Card vs Green Bay |
| CHI | Jahdae Walker | WR | Coach's Decision | Inactive for Wild Card vs Green Bay |
| CHI | Braxton Jones | OT | Knee | IR. Injured Reserve |
| CHI | R. Hyppolite II | LB | Coach's Decision | Inactive for Wild Card vs Green Bay |
| CHI | Joe Tryon-Shoyinka | DE | Concussion | Inactive for Wild Card vs Green Bay |
| CHI | Kiran Amegadjie | OT | Elbow | IR. Injured Reserve |
| CHI | Roschon Johnson | RB | Thumb | IR. Injured Reserve |
| CHI | Noah Sewell | LB | Achilles | IR. Injured Reserve |
| CHI | Dayo Odeyingbo | DE | Achilles | IR. Injured Reserve |
| CHI | Shemar Turner | DT | Knee - ACL | IR. Injured Reserve |
| CHI | Zah Frazier | CB | Personal | NFI-R for Wild Card vs Green Bay |
| CHI | Terell Smith | CB | Knee | IR. Injured Reserve |
| CHI | Deion Hankins | RB | Quadriceps | IR. Injured Reserve |
| CIN | Cordell Volson | G | Shoulder | IR. Injured Reserve |
| CIN | Erick All | TE | Knee - ACL | Physically Unable to Perform |
| CIN | Joseph Ossai | DE | Ankle | Questionable for start of Training Camp |
| CIN | Cam Grandy | TE | Chest | Questionable for start of Training Camp |
| CIN | Josh Newton | CB | Hamstring | Questionable for start of Training Camp |
| CIN | Charlie Jones | WR | Ankle | Questionable for start of Training Camp |
| CIN | Cam Taylor-Britt | CB | Foot | IR. Injured Reserve |
| CIN | DJ Turner | CB | Calf | Questionable for start of Training Camp |
| CIN | Matt Lee | C | Knee | IR. Injured Reserve |
| CIN | Brian Asamoah | LB | Knee | IR. Injured Reserve |
| CIN | Marco Wilson | CB | Hamstring | IR. Injured Reserve |
| CIN | Kris Jenkins | DT | Ankle | IR. Injured Reserve |
| CIN | Trey Hendrickson | DE | Pelvis | IR. Injured Reserve |
| CLE | DeAndre Carter | WR | Knee | IR. Injured Reserve |
| CLE | Denzel Ward | CB | Neck | Questionable for start of Training Camp |
| CLE | Luke Wypler | C | Knee | Questionable for start of Training Camp |
| CLE | Winston Reid | LB | Back | IR. Injured Reserve |
| CLE | Dom Jones | CB | Knee | IR. Injured Reserve |
| CLE | Carson Schwesinger | LB | Ankle | IR. Injured Reserve |
| CLE | Wyatt Teller | G | Calf | IR. Injured Reserve |
| CLE | Quinshon Judkins | RB | Ankle | IR. Injured Reserve |
| CLE | Jack Conklin | OT | Concussion | IR. Injured Reserve |
| CLE | Jerome Ford | RB | Shoulder | IR. Injured Reserve |
| CLE | Ethan Pocic | C | Achilles | IR. Injured Reserve |
| CLE | Maliek Collins | DT | Quadriceps | IR. Injured Reserve |
| CLE | Nathaniel Watson | LB | Biceps | IR. Injured Reserve |
| CLE | Martin Emerson | CB | Achilles | IR. Injured Reserve |
| CLE | Justin Osborne | C | Undisclosed | IR. Injured Reserve |
| CLE | Dawand Jones | OT | Knee | IR. Injured Reserve |
| CLE | Anthony Kendall | CB | Undisclosed | IR. Injured Reserve |
| CLE | Deshaun Watson | QB | Achilles | Physically Unable to Perform |
| CLE | Jeremiah Owusu-Koramoah | LB | Neck | Physically Unable to Perform |
| CLE | H. Fannin Jr. | TE | Groin | Questionable for start of Training Camp |
| CLE | David Njoku | TE | Knee | Questionable for start of Training Camp |
| CLE | Kingsley Eguakun | C | Knee | Questionable for start of Training Camp |
| DAL | S. Revel Jr. | CB | Concussion | Questionable for start of Training Camp |
| DAL | DeMarvion Overshown | LB | Concussion | Questionable for start of Training Camp |
| DAL | Tyler Smith | OT | Knee | Questionable for start of Training Camp |
| DAL | Alijah Clark | SAF | Personal | Questionable for start of Training Camp |
| DAL | Markquese Bell | SAF | Concussion | Questionable for start of Training Camp |
| DAL | Ajani Cornelius | OT | Knee | IR. Injured Reserve |
| DAL | Payton Turner | DE | Ribs | IR. Injured Reserve |
| DAL | Trevor Keegan | G | Neck | IR. Injured Reserve |
| DAL | Jack Sanborn | LB | Groin | IR. Injured Reserve |
| DAL | Javonte Williams | RB | Shoulder | IR. Injured Reserve |
| DAL | Malik Davis | RB | Eye | IR. Injured Reserve |
| DAL | T.J. Bass | G | Knee | IR. Injured Reserve |
| DAL | Tyler Guyton | OT | Ankle | IR. Injured Reserve |
| DAL | DaRon Bland | CB | Foot | IR. Injured Reserve |
| DAL | Juanyeh Thomas | SAF | Migraine | NFI-R for start of Training Camp |
| DAL | Miles Sanders | RB | Knee | IR. Injured Reserve |
| DAL | Robert Jones | G | Neck | IR. Injured Reserve |
| DEN | J.K. Dobbins | RB | Foot | IR. Injured Reserve |
| DEN | J. Walker Jr. | LB | Undisclosed | IR. Injured Reserve |
| DEN | Michael Burton | FB | Hamstring | IR. Injured Reserve |
| DEN | Nick Gargiulo | G | Knee | IR. Injured Reserve |
| DEN | Matt Henningsen | DE | Achilles | IR. Injured Reserve |
| DEN | John Franklin-Myers | DE | Hip | Questionable for Divisional Playoffs |
| DEN | Dre Greenlaw | LB | Hamstring | Questionable for Divisional Playoffs |
| DEN | Drew Sanders | LB | Foot | IR. Injured Reserve |
| DEN | Matt Peart | OT | Knee - MCL | IR. Injured Reserve |
| DEN | P.J. Locke | SAF | Leg | Questionable for Divisional Playoffs |
| DEN | Lucas Krull | TE | Foot | IR. Injured Reserve |
| DEN | Luke Wattenberg | C | Shoulder | IR. Injured Reserve |
| DEN | Brandon Jones | SAF | Pectoral | IR. Injured Reserve |
| DET | Zach Cunningham | ILB | Hamstring | IR. Injured Reserve |
| DET | Tom Kennedy | WR | Ribs | Questionable for start of Training Camp |
| DET | Giovanni Manu | OL | Knee | IR. Injured Reserve |
| DET | Brock Wright | TE | Neck | IR. Injured Reserve |
| DET | PortaSam LaPorta | TE | Back | IR. Injured Reserve |
| DET | Trystan Colon-Castillo | C | Wrist | IR. Injured Reserve |
| DET | Kerby Joseph | SAF | Knee | IR. Injured Reserve |
| DET | Brian Branch | SAF | Achilles | IR. Injured Reserve |
| DET | Terrion Arnold | CB | Shoulder | IR. Injured Reserve |
| DET | Josh Paschal | DE | Back | NFI-R for start of Training Camp |
| DET | Colby Sorsdal | G | Leg | IR. Injured Reserve |
| DET | Jamarco Jones | OT | Achilles | IR. Injured Reserve |
| DET | Kye Robichaux | RB | Undisclosed | IR. Injured Reserve |
| DET | E. Rakestraw Jr. | CB | Shoulder | IR. Injured Reserve |
| DET | Dan Jackson | SAF | Leg | IR. Injured Reserve |
| DET | Zeke Turner | LB | Foot | IR. Injured Reserve |
| DET | Levi Onwuzurike | DT | Knee - ACL | Physically Unable to Perform |
| DET | Kayode Awosika | OG | Illness | Questionable for start of Training Camp |
| DET | Alex Anzalone | MLB | Concussion | Questionable for start of Training Camp |
| DET | Alim McNeill | DT | Abdomen | Questionable for start of Training Camp |
| DET | Thomas Harper | SAF | Concussion | Questionable for start of Training Camp |
| DET | Penei Sewell | OT | Ankle | Questionable for start of Training Camp |
| GB | Zach Tom | G | Back | Inactive for Wild Card at Chicago |
| GB | Edgerrin Cooper | LB | Ankle | Questionable for Wild Card at Chicago |
| GB | Jacob Monk | C | Biceps | Questionable for Wild Card at Chicago |
| GB | Collin Oliver | LB | Coach's Decision | Inactive for Wild Card at Chicago |
| GB | Jakobie Keeney-James | WR | Coach's Decision | Inactive for Wild Card at Chicago |
| GB | Jaylin Simpson | CB | Coach's Decision | Inactive for Wild Card at Chicago |
| GB | Dontayvion Wicks | WR | Concussion | Inactive for Wild Card at Chicago |
| GB | John Williams | OG | Back | Physically Unable to Perform |
| GB | Elgton Jenkins | C | Lower Leg | IR. Injured Reserve |
| GB | Nick Niemann | LB | Pectoral | — |
| GB | Bo Melton | CB | Knee | IR. Injured Reserve |
| GB | Warren Brinson | DT | Foot | — |
| GB | Malik Willis | QB | Shoulder | — |
| GB | Javon Bullard | SAF | Knee | — |
| GB | Donovan Jennings | OT | Neck | IR. Injured Reserve |
| GB | Savion Williams | WR | Foot | IR. Injured Reserve |
| GB | Nate Hobbs | CB | Knee | IR. Injured Reserve |
| GB | Zayne Anderson | SAF | Ankle | IR. Injured Reserve |
| GB | Jordon Riley | DT | Achilles | IR. Injured Reserve |
| GB | Kamal Hadden | CB | Ankle | IR. Injured Reserve |
| GB | Kristian Welch | LB | Ankle | IR. Injured Reserve |
| GB | PatrickJohn FitzPatrick | TE | Achilles | IR. Injured Reserve |
| GB | MarShawn Lloyd | RB | Hamstring | IR. Injured Reserve |
| GB | Micah Parsons | DE | Knee - ACL | IR. Injured Reserve |
| GB | Devonte Wyatt | DT | Ankle | IR. Injured Reserve |
| GB | Tucker Kraft | TE | Knee - ACL | IR. Injured Reserve |
| GB | Travis Glover | OT | Shoulder | IR. Injured Reserve |
| HOU | Tim Settle | DT | Foot | IR. Injured Reserve |
| HOU | Joe Mixon | RB | Foot | NFI-R for Wild Card at Pittsburgh |
| HOU | M.J. Stewart | SAF | Quadriceps | IR. Injured Reserve |
| HOU | Kyonte Hamilton | DT | Ankle | IR. Injured Reserve |
| HOU | Brevin Jordan | TE | Knee | IR. Injured Reserve |
| HOU | Jawhar Jordan | RB | Ankle | Out for Wild Card at Pittsburgh |
| HOU | Jimmie Ward | SAF | Foot | Physically Unable to Perform. Expected Return - Week 19 |
| HOU | Tank Dell | WR | Knee - ACL + MCL | Physically Unable to Perform |
| HOU | Kurt Hinish | DT | Undisclosed | Physically Unable to Perform. Expected Return - Week 19 |
| HOU | Jaylen Reed | SAF | Forearm | IR. Injured Reserve. Expected Return - Week 19 |
| HOU | Tytus Howard | OT | Ankle | — |
| HOU | D. Stingley Jr. | CB | Oblique | — |
| HOU | Sheldon Rankins | DT | Elbow | — |
| HOU | Denico Autry | DT | Knee | — |
| HOU | Kamari Lassiter | CB | Ankle | — |
| HOU | Trent Brown | OT | Ankle | — |
| HOU | Jamal Hill | LB | Calf | — |
| HOU | Ajani Carter | DB | Hamstring | IR. Injured Reserve. Expected Return - Week 19 |
| HOU | Foley Fatukasi | DT | Shoulder | IR. Injured Reserve. Expected Return - Week 19 |
| HOU | Jake Hansen | LB | Chest | IR. Injured Reserve |
| HOU | Mario Edwards | DT | Pectoral | IR. Injured Reserve |
| HOU | Jaylin Smith | CB | Undisclosed | IR. Injured Reserve |
| IND | Cameron Mitchell | CB | Calf | Questionable for start of Training Camp |
| IND | Daniel Scott | SAF | Knee | IR. Injured Reserve |
| IND | Anthony Richardson | QB | Eye | IR. Injured Reserve |
| IND | Anthony Gould | WR | Foot | IR. Injured Reserve |
| IND | Braden Smith | OT | Concussion | IR. Injured Reserve |
| IND | Chris Lammons | DB | Foot | IR. Injured Reserve |
| IND | Andrew Ogletree | TE | Neck | IR. Injured Reserve |
| IND | Charvarius Ward | CB | Concussion | IR. Injured Reserve |
| IND | DeForest Buckner | DT | Neck | IR. Injured Reserve |
| IND | Daniel Jones | QB | Achilles | IR. Injured Reserve |
| IND | Salvon Ahmed | RB | Ankle | IR. Injured Reserve |
| IND | Spencer Shrader | K | Knee - ACL + MCL | IR. Injured Reserve |
| IND | Jack Wilson | OT | Undisclosed | IR. Injured Reserve |
| IND | Justin Walley | CB | Knee - ACL | IR. Injured Reserve |
| IND | Blake Freeland | OT | Leg | IR. Injured Reserve |
| IND | Jacob Phillips | LB | Biceps | IR. Injured Reserve |
| IND | D.J. Montgomery | WR | Undisclosed | IR. Injured Reserve |
| IND | Hunter Wohler | SAF | Foot | IR. Injured Reserve |
| IND | Sauce Gardner | CB | Calf | Questionable for start of Training Camp |
| IND | Will Mallory | TE | Chest | Questionable for start of Training Camp |
| JAC | Cooper Hodges | OT | Knee | Physically Unable to Perform. Expected Return - Week 19 |
| JAC | Montaric Brown | CB | Nose | — |
| JAC | G. Newsome II | CB | Shoulder | — |
| JAC | Danny Striggow | DE | Elbow | — |
| JAC | Jarrian Jones | CB | Illness | — |
| JAC | Jalen McLeod | LB | Ankle | IR. Injured Reserve |
| JAC | Patrick Mekari | OT | Back | — |
| JAC | Cole Van Lanen | OG | Knee | Questionable for Wild Card vs Buffalo |
| JAC | Jourdan Lewis | CB | Foot | IR. Injured Reserve |
| JAC | Jack Kiser | LB | Undisclosed | IR. Injured Reserve |
| JAC | Travis Hunter | WR | Knee | IR. Injured Reserve |
| JAC | Joshua Cephus | WR | Undisclosed | IR. Injured Reserve |
| JAC | Caleb Ransaw | CB | Lower Body | IR. Injured Reserve |
| KC | Omarr Norman-Lott | DT | Knee - ACL | IR. Injured Reserve |
| KC | Keaontay Ingram | RB | Undisclosed | IR. Injured Reserve |
| KC | Janarius Robinson | DE | Foot | IR. Injured Reserve |
| KC | E. Scott, Jr. | CB | Undisclosed | IR. Injured Reserve |
| KC | Brandon George | LB | Undisclosed | IR. Injured Reserve |
| KC | Deon Bush | SAF | Achilles | IR. Injured Reserve |
| KC | Felix Anudike-Uzomah | DE | Hamstring | IR. Injured Reserve |
| KC | Xavier Worthy | WR | Illness | Questionable for start of Training Camp |
| KC | Trey Smith | G | Ankle | Questionable for start of Training Camp |
| KC | Josh Simmons | OT | Wrist | IR. Injured Reserve |
| KC | Jake Briningstool | TE | Hamstring | IR. Injured Reserve |
| KC | Ethan Driskell | OT | Appendix | NFI-R for start of Training Camp |
| KC | Christian Roland-Wallace | CB | Back | IR. Injured Reserve |
| KC | Nikko Remigio | WR | Knee | IR. Injured Reserve |
| KC | Tyquan Thornton | WR | Concussion | IR. Injured Reserve |
| KC | Trent McDuffie | CB | Knee | IR. Injured Reserve |
| KC | Jaylen Watson | CB | Groin | IR. Injured Reserve |
| KC | Rashee Rice | WR | Concussion | IR. Injured Reserve |
| KC | Gardner Minshew | QB | Knee | IR. Injured Reserve |
| KC | Jawaan Taylor | OT | Elbow | IR. Injured Reserve |
| KC | Leo Chenal | LB | Shoulder | IR. Injured Reserve |
| KC | Patrick Mahomes | QB | Knee - ACL | IR. Injured Reserve |
| KC | Wanya Morris | OT | Knee | IR. Injured Reserve |
| LAC | Bud Dupree | OLB | Hamstring | Questionable for Wild Card at New England |
| LAC | Nikko Reed | CB | Hamstring | IR. Injured Reserve |
| LAC | Joe Alt | OT | Ankle | IR. Injured Reserve |
| LAC | Josh Fuga | DT | Undisclosed | IR. Injured Reserve |
| LAC | Rashawn Slater | OT | Kneecap | IR. Injured Reserve |
| LAC | Najee Harris | RB | Achilles | IR. Injured Reserve |
| LAC | Jordan Oladokun | CB | Undisclosed | IR. Injured Reserve |
| LAC | Junior Colson | LB | Shoulder | IR. Injured Reserve |
| LAC | Tucker Fisk | TE | Ankle | Questionable for Wild Card at New England |
| LAC | KeAndre Lambert-Smith | WR | Hamstring | IR. Injured Reserve |
| LAC | Savion Washington | OT | Undisclosed | Physically Unable to Perform |
| LAC | Kendall Williamson | SAF | Ankle | Out for Wild Card at New England |
| LAC | Austin Deculus | OT | Oblique | Questionable for Wild Card at New England |
| LAC | Del'Shawn Phillips | LB | Hamstring | Questionable for Wild Card at New England |
| LAC | Eric Rogers | CB | Undisclosed | IR. Injured Reserve |
| LAC | Elijah Molden | CB | Hamstring | Questionable for Wild Card at New England |
| LAC | Omarion Hampton | RB | Ankle | Questionable for Wild Card at New England |
| LAR | Darious Williams | CB | Coach's Decision | Inactive for Wild Card at Carolina |
| LAR | Matthew Stafford | QB | Finger | Questionable for Wild Card at Carolina |
| LAR | Jordan Whittington | WR | Knee | Inactive for Wild Card at Carolina |
| LAR | Ahkello Witherspoon | CB | Shoulder | Questionable for Wild Card at Carolina |
| LAR | Kevin Dotson | OG | Ankle | Inactive for Wild Card at Carolina |
| LAR | Derion Kendrick | CB | Coach's Decision | Inactive for Wild Card at Carolina |
| LAR | Josh Wallace | CB | Ankle | Inactive for Wild Card at Carolina |
| LAR | Stetson Bennett | QB | Coach's Decision | Inactive for Wild Card at Carolina |
| LAR | Terrance Ferguson | TE | Hamstring | Inactive for Wild Card at Carolina |
| LAR | Rob Havenstein | OT | Ankle | IR. Injured Reserve |
| LAR | Shaun Dolac | LB | Knee - PCL | IR. Injured Reserve |
| LAR | Keir Thomas | LB | Undisclosed | IR. Injured Reserve |
| LV | Kyu Blu Kelly | CB | Knee | IR. Injured Reserve |
| LV | Brennan Jackson | LB | Foot | IR. Injured Reserve |
| LV | Jackson Powers-Johnson | G | Ankle | IR. Injured Reserve |
| LV | Isaiah Pola-Mao | SAF | Shoulder | Questionable for start of Training Camp |
| LV | Kolton Miller | OT | Ankle | IR. Injured Reserve |
| LV | Brock Bowers | TE | Knee - PCL | IR. Injured Reserve |
| LV | Maxx Crosby | DE | Knee | IR. Injured Reserve |
| LV | Jeremy Chinn | SAF | Back | IR. Injured Reserve |
| LV | Jordan Meredith | C | Ankle | IR. Injured Reserve |
| LV | Geno Smith | QB | Ankle | Questionable for start of Training Camp |
| LV | Dylan Parham | OG | Illness | Questionable for start of Training Camp |
| LV | Raheem Mostert | RB | Knee | Questionable for start of Training Camp |
| LV | Adam Butler | DT | Biceps | Questionable for start of Training Camp |
| MIA | Liam Eichenberg | OT | Knee | Physically Unable to Perform |
| MIA | Minkah Fitzpatrick | FS | Calf | Questionable for start of Training Camp |
| MIA | De'Von Achane | RB | Shoulder | Questionable for start of Training Camp |
| MIA | Austin Jackson | OT | Back | Questionable for start of Training Camp |
| MIA | Jaylen Waddle | WR | Ribs | Questionable for start of Training Camp |
| MIA | Chop Robinson | LB | Concussion | Questionable for start of Training Camp |
| MIA | Julius Brents | CB | Foot | IR. Injured Reserve |
| MIA | Storm Duck | CB | Knee | IR. Injured Reserve |
| MIA | Jason Maitre | DB | Undisclosed | IR. Injured Reserve |
| MIA | Alexander Mattison | RB | Neck | IR. Injured Reserve |
| MIA | Jalin Conyers | TE | Leg | IR. Injured Reserve |
| MIA | Kader Kohou | CB | Knee - ACL | IR. Injured Reserve |
| MIA | Germain Ifedi | OT | Undisclosed | IR. Injured Reserve |
| MIA | Artie Burns | CB | Knee - ACL | IR. Injured Reserve |
| MIA | Tyreek Hill | WR | Knee - ACL | IR. Injured Reserve |
| MIA | Yodny Cajuste | OT | Undisclosed | IR. Injured Reserve |
| MIA | Obinna Eze | OT | Undisclosed | IR. Injured Reserve |
| MIA | T. Wease Jr. | WR | Head | Questionable for start of Training Camp |
| MIA | Quinn Ewers | QB | Knee | Questionable for start of Training Camp |
| MIA | Jordan Colbert | SAF | Neck | IR. Injured Reserve |
| MIA | Jason Sanders | K | Hip | IR. Injured Reserve |
| MIA | Malik Washington | WR | Thumb | Questionable for start of Training Camp |
| MIA | Darren Waller | TE | Groin | IR. Injured Reserve |
| MIA | Caleb Johnson | LB | Shoulder | IR. Injured Reserve |
| MIA | Isaiah Johnson | CB | Knee | IR. Injured Reserve |
| MIA | D'Wayne Eskridge | WR | Toe | IR. Injured Reserve |
| MIA | Benito Jones | DT | Back | IR. Injured Reserve |
| MIA | James Daniels | G | Pectoral | IR. Injured Reserve |
| MIA | Elijah Campbell | DB | Ankle | IR. Injured Reserve |
| MIN | Josh Oliver | TE | Ankle | Questionable for start of Training Camp |
| MIN | Jeff Okudah | CB | Concussion | IR. Injured Reserve |
| MIN | J.J. McCarthy | QB | Hand | Questionable for start of Training Camp |
| MIN | Elijah Williams | DE | Ankle | IR. Injured Reserve |
| MIN | Ryan Kelly | C | Concussion | IR. Injured Reserve |
| MIN | Christian Darrisaw | OT | Knee | IR. Injured Reserve |
| MIN | Jonathan Greenard | LB | Shoulder | IR. Injured Reserve |
| MIN | Josh Metellus | SAF | Shoulder | IR. Injured Reserve |
| MIN | Gavin Bartholomew | TE | Back | Physically Unable to Perform |
| MIN | Aaron Jones | RB | Hip | Questionable for start of Training Camp |
| MIN | T.J. Hockenson | TE | Shoulder | Questionable for start of Training Camp |
| MIN | Dwight McGlothern | CB | Hip | Questionable for start of Training Camp |
| MIN | Myles Price | WR | Ankle | Questionable for start of Training Camp |
| MIN | Carson Wentz | QB | Shoulder | IR. Injured Reserve |
| MIN | Rondale Moore | WR | Knee | IR. Injured Reserve |
| MIN | Zeke Correll | C | Ankle | IR. Injured Reserve |
| MIN | Matt Nelson | OT | Undisclosed | IR. Injured Reserve |
| NE | Antonio Gibson | RB | Knee - ACL | IR. Injured Reserve |
| NE | Deneric Prince | RB | Undisclosed | IR. Injured Reserve |
| NE | Yasir Durant | OT | Undisclosed | IR. Injured Reserve |
| NE | Jaquelin Roy | DT | Undisclosed | IR. Injured Reserve |
| NE | Brock Lampe | RB | Undisclosed | IR. Injured Reserve |
| NE | Marcellas Dial | CB | Knee - ACL | IR. Injured Reserve |
| NE | Lan Larison | RB | Foot | IR. Injured Reserve |
| NE | Isaiah Iton | DT | Hip | IR. Injured Reserve |
| NE | Mack Hollins | WR | Abdomen | IR. Injured Reserve |
| NE | Joshua Farmer | DT | Hamstring | IR. Injured Reserve |
| NE | Alex Austin | CB | Wrist | IR. Injured Reserve |
| NE | Kayshon Boutte | WR | Hamstring | Questionable for Wild Card vs L.A. Chargers |
| NE | Khyiris Tonga | DT | Foot | Out for Wild Card vs L.A. Chargers |
| NE | Thayer Munford | OT | Knee | Questionable for Wild Card vs L.A. Chargers |
| NE | Vederian Lowe | OT | Illness | — |
| NE | Garrett Bradbury | C | Illness | — |
| NE | Terrell Jennings | RB | Concussion | IR. Injured Reserve |
| NE | Harold Landry | LB | Knee | Questionable for Wild Card vs L.A. Chargers |
| NE | Jared Wilson | OG | Concussion | — |
| NO | Taysom Hill | TE | Shoulder - AC Joint | Questionable for start of Training Camp |
| NO | Nathan Shepherd | DT | Ankle | Questionable for start of Training Camp |
| NO | Chris Olave | WR | Illness | Questionable for start of Training Camp |
| NO | Alvin Kamara | RB | Knee - MCL | Questionable for start of Training Camp |
| NO | Spencer Rattler | QB | Finger | Questionable for start of Training Camp |
| NO | Bryan Bresee | DT | Knee | Questionable for start of Training Camp |
| NO | Julian Blackmon | SAF | Shoulder - Labrum | IR. Injured Reserve |
| NO | Erik McCoy | C | Biceps | IR. Injured Reserve |
| NO | Kendre Miller | RB | Knee - ACL | IR. Injured Reserve |
| NO | Bub Means | WR | Lower Leg | IR. Injured Reserve |
| NO | Landon Young | OT | Ankle | IR. Injured Reserve |
| NO | Mason Pline | TE | Upper Body | IR. Injured Reserve |
| NO | Ja'Lynn Polk | WR | Shoulder | IR. Injured Reserve |
| NO | Will Clapp | C | Foot | IR. Injured Reserve |
| NO | Nick Saldiveri | G | Knee | IR. Injured Reserve |
| NO | Vernon Broughton | DT | Hip | IR. Injured Reserve |
| NO | K. Banks Jr. | OT | Ankle | Questionable for start of Training Camp |
| NO | Trey Palmer | WR | Ankle | IR. Injured Reserve |
| NO | Mason Tipton | WR | Groin | IR. Injured Reserve |
| NO | Jack Stoll | TE | Knee | IR. Injured Reserve |
| NO | Michael Davis | CB | Shoulder | IR. Injured Reserve |
| NO | Zaire Mitchell-Paden | TE | Knee | IR. Injured Reserve |
| NO | Foster Moreau | TE | Ankle | IR. Injured Reserve |
| NO | Devaughn Vele | WR | Shoulder | IR. Injured Reserve |
| NO | Devin Neal | RB | Hamstring | IR. Injured Reserve |
| NYG | Darius Muasau | LB | Ankle | Questionable for start of Training Camp |
| NYG | T. Fidone II | TE | Foot | IR. Injured Reserve |
| NYG | Rico Payton | CB | Head | Questionable for start of Training Camp |
| NYG | Micah McFadden | LB | Foot | IR. Injured Reserve |
| NYG | Evan Neal | OT | Neck | IR. Injured Reserve |
| NYG | Chris Board | LB | Chest | IR. Injured Reserve |
| NYG | Wan'Dale Robinson | WR | Ribs | IR. Injured Reserve |
| NYG | Cordale Flott | CB | Knee | IR. Injured Reserve |
| NYG | Rakeem Nunez-Roches | DT | Ankle | IR. Injured Reserve |
| NYG | Joshua Ezeudu | G | Calf | IR. Injured Reserve |
| NYG | Beaux Collins | WR | Concussion | IR. Injured Reserve |
| NYG | Andrew Thomas | OT | Hamstring | IR. Injured Reserve |
| NYG | Tyler Nubin | SAF | Neck | IR. Injured Reserve |
| NYG | John Michael Schmitz | C | Finger | IR. Injured Reserve |
| NYG | D.J. Davidson | DT | Neck | IR. Injured Reserve |
| NYG | Kayvon Thibodeaux | LB | Shoulder | IR. Injured Reserve |
| NYG | Nic Jones | CB | Shoulder | IR. Injured Reserve |
| NYG | Victor Dimukeje | LB | Knee | IR. Injured Reserve |
| NYG | A. Johnson Jr. | SAF | Undisclosed | Physically Unable to Perform |
| NYG | Jevon Holland | SAF | Knee | Questionable for start of Training Camp |
| NYG | Jalin Hyatt | WR | Illness | Questionable for start of Training Camp |
| NYG | Theo Johnson | TE | Illness | Questionable for start of Training Camp |
| NYG | Graham Gano | K | Neck | IR. Injured Reserve |
| NYG | Cam Skattebo | RB | Ankle | IR. Injured Reserve |
| NYG | Malik Nabers | WR | Knee - ACL | IR. Injured Reserve |
| NYG | TJ Moore | CB | Upper Leg | IR. Injured Reserve |
| NYG | Bryce Ford-Wheaton | WR | Achilles | IR. Injured Reserve |
| NYG | Da'Quan Felton | WR | Undisclosed | IR. Injured Reserve |
| NYJ | Tyler Baron | DE | Knee | IR. Injured Reserve |
| NYJ | Kris Boyd | CB | Abdomen | IR. Injured Reserve |
| NYJ | Andre Cisco | SAF | Pectoral | IR. Injured Reserve |
| NYJ | Gus Hartwig | C | Undisclosed | IR. Injured Reserve |
| NYJ | Alijah Vera-Tucker | G | Triceps | IR. Injured Reserve |
| NYJ | Josh Reynolds | WR | Hip | IR. Injured Reserve |
| NYJ | J. Brownlee Jr. | CB | Hip | IR. Injured Reserve |
| NYJ | Braelon Allen | RB | Knee - MCL | IR. Injured Reserve |
| NYJ | Marcelino McCrary-Ball | LB | Hamstring | IR. Injured Reserve |
| NYJ | Quincy Williams | LB | Hand | Questionable for start of Training Camp |
| NYJ | Isaiah Davis | RB | Concussion | IR. Injured Reserve |
| NYJ | Xavier Newman-Johnson | G | Knee | IR. Injured Reserve |
| NYJ | Mason Taylor | TE | Neck | IR. Injured Reserve |
| NYJ | Francisco Mauigoa | LB | Neck | IR. Injured Reserve |
| NYJ | W. McDonald IVWill McDonald IV | DE | Knee | IR. Injured Reserve |
| NYJ | Jay Tufele | DT | Foot | IR. Injured Reserve |
| NYJ | Justin Fields | QB | Knee | IR. Injured Reserve |
| NYJ | Garrett Wilson | WR | Knee | IR. Injured Reserve |
| NYJ | Tony Adams | SAF | Groin | IR. Injured Reserve |
| NYJ | Isaiah Oliver | SAF | Knee | IR. Injured Reserve |
| NYJ | Azareye'h Thomas | CB | Shoulder | IR. Injured Reserve |
| NYJ | Irvin Charles | WR | Knee - ACL | Physically Unable to Perform |
| NYJ | Micheal Clemons | DE | Ankle | Questionable for start of Training Camp |
| NYJ | Breece Hall | RB | Knee | Questionable for start of Training Camp |
| NYJ | Brandon Stephens | CB | Neck | Questionable for start of Training Camp |
| NYJ | Jelani Woods | TE | Hamstring | Questionable for start of Training Camp |
| NYJ | Tyrod Taylor | QB | Knee | Questionable for start of Training Camp |
| NYJ | Qwan'tez Stiggers | CB | Knee | Questionable for start of Training Camp |
| PHI | Azeez Ojulari | LB | Hamstring | IR. Injured Reserve |
| PHI | Brett Toth | G | Concussion | Out for Wild Card vs San Francisco |
| PHI | Marcus Epps | SAF | Concussion | — |
| PHI | Dallas Goedert | TE | Knee | — |
| PHI | Lane Johnson | OT | Foot | Questionable for Wild Card vs San Francisco |
| PHI | Jalen Carter | DT | Hip | — |
| PHI | Myles Hinton | OT | Back | IR. Injured Reserve |
| PHI | Willie Lampkin | G | Knee | IR. Injured Reserve |
| PHI | Obo Okoronkwo | DE | Triceps | IR. Injured Reserve |
| PHI | Johnny Wilson | WR | Knee | IR. Injured Reserve |
| PHI | Andrew Mukuba | SAF | Ankle | IR. Injured Reserve. Expected Return - Week 19 |
| PHI | Grant Calcaterra | TE | Ankle | — |
| PHI | SumerenBen VanSumeren | RB | Knee | IR. Injured Reserve. Expected Return - Week 19 |
| PIT | Skylar Thompson | QB | Hamstring | IR. Injured Reserve. Expected Return - Week 19 |
| PIT | Calvin Anderson | OT | Knee | IR. Injured Reserve. Expected Return - Week 19 |
| PIT | DeShon Elliott | SAF | Knee | IR. Injured Reserve. Expected Return - Week 19 |
| PIT | Darnell Washington | TE | Forearm | IR. Injured Reserve |
| PIT | Isaiahh Loudermilk | DT | Ankle | IR. Injured Reserve |
| PIT | Jonnu Smith | TE | Lower Body | — |
| PIT | Jaylen Warren | RB | Illness | — |
| PIT | Donte Kent | CB | Ankle | IR. Injured Reserve |
| PIT | Broderick Jones | OT | Neck | IR. Injured Reserve |
| PIT | Cory Trice | CB | Knee | IR. Injured Reserve |
| PIT | Daniel Ekuale | DT | Knee - ACL | IR. Injured Reserve |
| PIT | Miles Killebrew | SAF | Knee | IR. Injured Reserve |
| PIT | Dean Lowry | DT | Knee | IR. Injured Reserve |
| PIT | Jacob Slade | DT | Undisclosed | IR. Injured Reserve |
| PIT | D. Parham Jr. | TE | Achilles | IR. Injured Reserve |
| PIT | Max Scharping | G | Knee | IR. Injured Reserve |
| SEA | AJ Finley | SAF | Knee | IR. Injured Reserve |
| SEA | Kenny McIntosh | RB | Knee - ACL | IR. Injured Reserve |
| SEA | George Holani | RB | Hamstring | IR. Injured Reserve |
| SEA | Tory Horton | WR | Shin | IR. Injured Reserve |
| SEA | Chazz Surratt | LB | Ankle | IR. Injured Reserve |
| SEA | Cody White | WR | Groin | IR. Injured Reserve |
| SEA | Elijah Arroyo | TE | Knee | IR. Injured Reserve |
| SEA | Charles Cross | OT | Hamstring | Questionable for Divisional Playoffs |
| SEA | Coby Bryant | SAF | Knee | Questionable for Divisional Playoffs |
| SF | Jacob Cowing | WR | Hamstring | IR. Injured Reserve |
| SF | Renardo Green | CB | Ankle | Questionable for Wild Card at Philadelphia |
| SF | Ben Bartch | OT | Foot | IR. Injured Reserve |
| SF | Tatum Bethune | LB | Groin | IR. Injured Reserve |
| SF | George Kittle | TE | Ankle | — |
| SF | Jordan Elliott | DT | Knee | — |
| SF | Keion White | DE | Groin | Questionable for Wild Card at Philadelphia |
| SF | Yetur Gross-Matos | DE | Knee | — |
| SF | Trent Williams | OT | Hamstring | Questionable for Wild Card at Philadelphia |
| SF | Luke Gifford | LB | Quadriceps | Questionable for Wild Card at Philadelphia |
| SF | Ricky Pearsall | WR | Knee - PCL | Questionable for Wild Card at Philadelphia |
| SF | Mykel Williams | DE | Knee - ACL | IR. Injured Reserve |
| SF | Tarron Jackson | DE | Undisclosed | IR. Injured Reserve |
| SF | Trent Taylor | WR | Undisclosed | IR. Injured Reserve |
| SF | Jakob Robinson | CB | Forearm | IR. Injured Reserve |
| SF | Patrick Taylor | RB | Shoulder | IR. Injured Reserve |
| SF | Tre'Vius Hodges-Tomlinson | CB | Undisclosed | IR. Injured Reserve |
| SF | Nick Bosa | DE | Knee - ACL | IR. Injured Reserve |
| SF | Dee Winters | LB | Ankle | Questionable for Wild Card at Philadelphia |
| SF | Kurtis Rourke | QB | Knee | NFI-R for Wild Card at Philadelphia |
| SF | Fred Warner | MLB | Ankle | IR. Injured Reserve |
| SF | Nick Martin | LB | Concussion | IR. Injured Reserve |
| TB | Anthony Walker | MLB | Ankle | Questionable for start of Training Camp |
| TB | Ben Bredeson | G | Knee | IR. Injured Reserve |
| TB | Zyon McCollum | CB | Hip | IR. Injured Reserve |
| TB | Jamel Dean | CB | Shoulder | Questionable for start of Training Camp |
| TB | Anthony Nelson | LB | Knee | Questionable for start of Training Camp |
| TB | J.J. Roberts | SAF | Knee | IR. Injured Reserve |
| TB | David Walker | LB | Knee | IR. Injured Reserve |
| TB | Ko Kieft | TE | Leg | IR. Injured Reserve |
| TB | Jaden Smith | WR | Undisclosed | IR. Injured Reserve |
| TB | Cody Mauch | G | Knee | IR. Injured Reserve |
| TEN | Calvin Ridley | WR | Lower Leg | IR. Injured Reserve |
| TEN | Anfernee Orji | LB | Knee - ACL | IR. Injured Reserve |
| TEN | Will Levis | QB | Shoulder | IR. Injured Reserve |
| TEN | Corey Levin | OG | Biceps | Questionable for start of Training Camp |
| TEN | Kevin Zeitler | OG | Quadriceps | Questionable for start of Training Camp |
| TEN | L'Jarius Sneed | CB | Quadriceps | IR. Injured Reserve |
| TEN | Blake Hance | OL | Shoulder | IR. Injured Reserve |
| TEN | Van Jefferson | WR | Forearm | IR. Injured Reserve |
| TEN | Jalyn Armour-Davis | CB | Achilles | IR. Injured Reserve |
| TEN | Oluwafemi Oladejo | LB | Lower Leg | IR. Injured Reserve |
| TEN | Marcus Harris | CB | Knee | IR. Injured Reserve |
| TEN | K. Winston Jr. | SAF | Hamstring | IR. Injured Reserve |
| TEN | Xavier Woods | FS | Hamstring | IR. Injured Reserve |
| TEN | Mike Brown | SAF | Ankle | IR. Injured Reserve |
| TEN | James Williams | LB | Shoulder - AC Joint | Questionable for start of Training Camp |
| TEN | Cam Ward | QB | Shoulder - AC Joint | Questionable for start of Training Camp |
| TEN | Amani Hooker | SAF | Ankle | Questionable for start of Training Camp |
| TEN | Arden Key | LB | Hip | Questionable for start of Training Camp |
| TEN | Gunnar Helm | TE | Toe | Questionable for start of Training Camp |
| WAS | Laremy Tunsil | OT | Oblique | Questionable for start of Training Camp |
| WAS | Jayden Daniels | QB | Elbow | Questionable for start of Training Camp |
| WAS | Marcus Mariota | QB | Hand | Questionable for start of Training Camp |
| WAS | Tyler Biadasz | C | Knee | IR. Injured Reserve |
| WAS | Eddie Goldman | NT | Concussion | IR. Injured Reserve |
| WAS | Samuel Cosmi | G | Concussion | IR. Injured Reserve |
| WAS | Jaylin Lane | WR | Ankle | IR. Injured Reserve |
| WAS | Javontae Jean-Baptiste | DE | Pectoral | IR. Injured Reserve |
| WAS | Trey Amos | CB | Lower Leg | IR. Injured Reserve |
| WAS | Noah Brown | WR | Ribs | IR. Injured Reserve |
| WAS | Luke McCaffrey | WR | Collarbone | IR. Injured Reserve |
| WAS | Zach Ertz | TE | Knee - ACL | IR. Injured Reserve |
| WAS | Marshon Lattimore | CB | Knee - ACL | IR. Injured Reserve |
| WAS | Dorance Armstrong | DE | Knee | IR. Injured Reserve |
| WAS | Lucas Niang | OT | Knee - ACL | IR. Injured Reserve |
| WAS | Tyree Jackson | TE | Undisclosed | IR. Injured Reserve |
| WAS | D. Wise Jr. | DE | Quadriceps | IR. Injured Reserve |
| WAS | Austin Ekeler | RB | Achilles | IR. Injured Reserve |