Date: Monday, November 3, 2025
Time: 8:30 PM EST
Venue: Enterprise Center, St. Louis, MO
Moneyline Odds: Oilers -144, Blues +120
The Edmonton Oilers travel to St. Louis for a Western Conference showdown against a Blues team dealing with a significant new injury. The Oilers enter as road favorites, but they are not without their own injury concerns as they look to secure a win at the Enterprise Center.
Edmonton Oilers Analysis
The Oilers hit the road as -144 favorites, but their lineup has been hampered by recent injuries. According to a report from five days ago, forward Trent Frederic re-aggravated a previous ankle injury and was absent from practice. This continues a frustrating recovery for Frederic, who was acquired while already nursing the injury.
Adding to the uncertainty, Zach Hyman was sidelined with a wrist injury in late October, forcing him to miss at least two games. While his status for Monday’s contest is not specified in the provided information, his recent absence is a point of concern for Edmonton’s forward depth. The team will need its top-end talent to overcome these potential absences.
St. Louis Blues Analysis
The Blues are home underdogs at +120, a line likely influenced by a major injury blow to their roster. A report from six days ago announced that forward Jake Neighbours has been placed on the injured list and is expected to be sidelined for five weeks. His absence will be a significant challenge for the Blues to overcome.
The team has also faced other recent injury questions. In mid-October, forward Alexey Toropchenko was listed as questionable with an upper and lower-body injury. His current status for this matchup is unknown, adding another layer of uncertainty to the Blues’ lineup as they prepare to face the high-powered Oilers.
Prediction
Both teams are entering this game with key players on the injury report. However, the news for St. Louis appears more definitive and impactful. The loss of Jake Neighbours for over a month is a significant blow to the Blues’ offense.
While the Oilers are dealing with injuries to Trent Frederic and potentially Zach Hyman, their core offensive drivers remain. The betting line reflects this, favoring Edmonton even on the road. The Blues will struggle to replace the production of Neighbours, giving the Oilers the definitive edge in this matchup.
The Pick: Edmonton Oilers (-144)
The Over/Under is set at 6.5 goals. With key forwards injured on both sides, particularly the confirmed absence of Neighbours, this game could be a tighter, lower-scoring affair than a typical Oilers contest. The Under 6.5 (+100) presents good value.
Sources:
Edmonton Oilers Injury Status – ESPN
Edmonton Oilers Injury Report and Status 2025-26 – CBS Sports
Oilers Injury Report: Trent Frederic, Evander Kane, Connor McDavid …
Oilers Injury Report: Trent Frederic, Evander Kane, Connor McDavid
Edmonton Oilers Injury Status – ESPN (AU)
Oilers Injury Report: Mattias Ekholm & Calvin Pickard
Oilers Injury Report: Leon Draisaitl & Trent Frederic – Yahoo Sports
Oilers Injury Report: Connor McDavid & Stuart Skinner
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