Game Date: 2025-04-04
Matchup: San Diego Padres at Chicago Cubs
Location: Wrigley Field, Chicago, Illinois
Time: 2:20 PM ET / 6:20 PM UTC
Pitching Matchup:
- Padres: Randy Vásquez (RHP)
- Cubs: Shota Imanaga (LHP)
Moneyline Odds:
- Padres: +142
- Cubs: -170
Preview:
The San Diego Padres travel to the historic Wrigley Field to face off against the Chicago Cubs on Friday, April 4, 2025. This early season matchup pits two National League teams looking to establish momentum as the season gets underway.
On the mound, we have an intriguing pitching duel. The Padres will send right-hander Randy Vásquez to the hill. Facing him for the Cubs will be left-handed pitcher Shota Imanaga. This contrast in pitching styles could be a key factor in the game’s outcome.
The Cubs enter this game as the favorites, reflected in their -170 moneyline odds. Playing at home in front of their passionate fanbase at Wrigley Field certainly gives them an advantage. The Padres, listed as underdogs at +142, will be looking to play spoiler and secure a road victory.
Recent snippets suggest this game is generating considerable interest, with multiple outlets offering previews, predictions, and viewing information. While specific predictions are not explicitly provided in these snippets, the odds clearly indicate that oddsmakers favor the Cubs in this contest.
How to Watch:
First pitch is scheduled for 2:20 PM Eastern Time. Check local listings for TV coverage as well as streaming options to catch all the action from Wrigley Field.
Prediction:
While the snippets don’t give a definitive expert pick, the Cubs are clearly favored at home with Shota Imanaga on the mound. Left-handed pitching can sometimes pose a challenge for Padres lineups historically. Therefore, leaning towards the Cubs to win at home seems like the safer prediction based on the available information and odds. However, baseball is unpredictable, and Randy Vásquez could certainly deliver a strong performance for the Padres to upset the odds.
Keep an eye on: The effectiveness of Imanaga’s left-handed pitching against the Padres lineup and whether Vásquez can silence the Cubs’ bats in the Wrigley Field environment.
Sources:
Statcast Game Preview: San Diego Padres at Chicago Cubs – 2025 …
Cubs vs. Padres Prediction, Odds, Picks – April 4 | FOX Sports
Cubs vs Padres live score & predictions | Sofascore
How to Watch Cubs vs. Padres: TV Channel & Live Stream – April 4 …
Cubs vs Padres Expert Pick and Prediction – April 4
Padres vs. Cubs prediction, odds, pick – 4/4/2025
Padres at Cubs Prediction: Odds, expert picks, starting pitchers …
San Diego Padres vs Chicago Cubs – Game Center – 2025-04-04 …
San Diego Padres vs. Chicago Cubs Live Coverage, Stats, and …
San Diego Padres vs Chicago Cubs – Game Centre – 2025/04/04 …